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Primotren (Trimethoprim)

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Primotren (sulfamethoxazole / trimethoprim) is absorbed by the body and begins to kill bacteria within 1 to 4 hours after taking your dose. For more common problems like urinary tract infections and ear infections, most people will start to feel relief after a few days.

Other names for this medication:
Assepium, Bactoprim, Bactricida, Bactron, Bactropin, Bascul, Biseptrin, Bitrim, Cadiprim, Comox, Cotrimol, Cozole, Danferane, Droxol, Drylin, Gentrim, Ikaprim, Infatrim, Infectrin, Kepinol, Lapikot, Medibiot, Neotrim, Nopil, Novotrim, Politrim, Primazole, Sitrim, Sulfoprima, Trimecor, Trimezol, Trimoks, Trizole, Urisept

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Also known as: Trimethoprim


Primotren contains a combination of sulfamethoxazole and trimethoprim. Sulfamethoxazole and trimethoprim are are both antibiotics that treat different types of infection caused by bacteria.

Primotren is used to treat ear infections, urinary tract infections, bronchitis, traveler's diarrhea, shigellosis, and Pneumocystis jiroveci pneumonia.


Adults: The usual adult dosage in the treatment of urinary tract infections is 1 Primotren DS (double strength) tablet or 2 Primotren tablets every 12 hours for 10 to 14 days. An identical daily dosage is used for 5 days in the treatment of shigellosis.

Children: The recommended dose for children with urinary tract infections or acute otitis media is 40 mg/kg sulfamethoxazole and 8 mg/kg trimethoprim per 24 hours, given in two divided doses every 12 hours for 10 days. An identical daily dosage is used for 5 days in the treatment of shigellosis.


If you overdose Generic Primotren and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Primotren overdosage: dizziness, drowsiness, nausea, vomiting, loss of appetite, stomach pain, headache, yellowing of your skin or eyes, blood in urine, fever, confusion, fainting.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Side effects

The most common side effects associated with Primotren are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Primotren is contraindicated in patients with a known hypersensitivity to trimethoprim or sulfonamides, in patients with a history of drug-induced immune thrombocytopenia with use of trimethoprim and/or sulfonamides, and in patients with documented megaloblastic anemia due to folate deficiency.

Primotren is contraindicated in pediatric patients less than 2 months of age. Primotren is also contraindicated in patients with marked hepatic damage or with severe renal insufficiency when renal function status cannot be monitored.

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Porphyrin homeostasis is required because absence of the porphyrin exporter, ABCG2, increased death of leukemic progenitors in vitro and prolonged the survival of mice transplanted with Abcg2-KO MYCN-HPCs. Genetic interaction analysis of TCF7L2 for biochemical recurrence after radical prostatectomy in localized prostate cancer. IGF-I receptor (IGF-IR) signaling and functions are mediated through the activities of a complex molecular network of positive (e.g., type I IGF) and negative (e.g., the type II IGF receptor, IGF-IIR) effectors. Further investigation revealed that wogonin activated ERK and p38 MAPKs, which was inhibited by N-acetyl cysteine (NAC), a ROS scavenger, indicating that wogonin-induced ROS are associated with MAPKs activation. We report on a patient with acquired immunodeficiency syndrome who presented with Aspergillus myo-fasciitis, which was unusual because of its relapsing-remitting course and favorable outcome. Results indicated that both cord blood leukocytes and those from individuals over 70 were significantly lower (P less than 0.05) in their chemiluminescence response. Comparison of intraocular pressure reducing effects of three prostaglandin eyedrops in open-angle glaucoma. Quinine is a common cause of drug-associated TTP-HUS and can cause death and chronic renal failure. Biopsies following the high transfusion regime showed progressive increase in the size and number of iron-containing lysosomes in both parenchymal and sinusoidal cells.

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At the same time, 32 of the 48 patients had a bone scan and 26 of the 48 patients had abdominal-pelvic diagnostic CT. General practice trainees in this study have a low opinion of how WPBA assessments function in the hospital setting. A case of a traumatic chyle leak following an acute thoracic spine injury: successful resolution with strict dietary manipulation. Functional interaction between 5-HT(6) receptors and hypothalamic-pituitary-adrenal axis: cognitive implications. There has been booming interest in laparoscopic surgery for colorectal cancer since 2006 in China. Superficial femoral vein thrombosis: a potentially confusing term. The role of ataxin 10 in the pathogenesis of spinocerebellar ataxia type 10. Reduction of SM abrogated TrkB activation in mature neurons, whereas increasing SM in immature neurons triggered receptor activation. An index of repetition-induced summation of pain was derived as the change in pain ratings across repeated lifts.

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