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Digobal (Digoxin)

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Digobal is a type of drug called a cardiac glycoside. Their function is to slow your heart rate down and improve the filling of your ventricles (two of the chambers of the heart) with blood. For people with atrial fibrillation, where the heart beats irregularly, a different volume of blood is pumped out each time.

Other names for this medication:
Agoxin, Cardiacin, Cardiogoxin, Digacin, Digibind, Digitek, Digobal, Digohan, Digoregen, Digosin, Digossina, Digoxen, Digoxin, Digoxine, Digoxinum, Eudigox, Fargoxin, Halfdigoxin, Lanadicor, Lanibos, Lanicor, Lenoxin, Purgoxin, Sigmaxin, Vidaxil

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Also known as: Digoxin


Digoxin is used to treat congestive heart failure, usually in combination with a diuretic (water pill) and an angiotensin-converting enzyme (ACE) inhibitor. It is also used to treat a heart rhythm problem called atrial fibrillation.

Digoxin belongs to the class of medicines called digitalis glycosides. It is used to improve the strength and efficiency of the heart, or to control the rate and rhythm of the heartbeat. This leads to better blood circulation and reduced swelling of the hands and ankles in patients with heart problems.

This medicine is available only with your doctor's prescription.


Usual Adult Dose of Digobal for Congestive Heart Failure:

Rapid Digitalization with a Loading Dose: Peak digoxin body stores of 8 to 12 mcg/kg generally provide a therapeutic effect with minimum risk of toxicity in most patients with heart failure and normal sinus rhythm. The loading dose should be administered in several fractions, with approximately half the total given as the first dose. Additional fractions of the total dose may be given at 6 to 8 hour intervals. Careful assessment of the patient's clinical response should be considered before each additional dose. If the patient's response necessitates a change from the calculated loading dose of digoxin, then calculation of the maintenance dose should be based upon the amount actually given. Tablets: Initial: 500 to 750 mcg usually produces a detectable effect in 0.5 to 2 hours with a maximal effect in 2 to 6 hours. Additional doses of 125 to 375 mcg may be given at 6 to 8 hour intervals until clinical evidence of an adequate effect is noted. The usual amount of digoxin tablets that a 70 kg patient requires to achieve 8 to 12 mcg/kg peak body stores is 750 to 1250 mcg. Injection: Initial: 400 to 600 mcg of digoxin intravenously usually produces a detectable effect in 5 to 30 minutes with a maximal effect in 1 to 4 hours. Additional doses of 100 to 300 mcg may be given cautiously at 6 to 8 hour intervals until clinical evidence of an adequate effect is noted. The usual amount of digoxin injection that a 70 kg patient requires to achieve 8 to 12 mcg/kg peak body stores is 600 to 1000 mcg. The injectable route is frequently used to achieve rapid digitalization, with conversion to digoxin tablets for maintenance therapy. Maintenance Dose: The doses of digoxin tablets used in controlled trials in patients with heart failure have ranged from 125 to 500 mcg once daily. In these studies, the digoxin dose has been generally titrated according to the patient's age, lean body weight, and renal function. Therapy is generally initiated at a dose of 250 mcg once daily in patients under age 70 with good renal function.

Usual Adult Dose for Atrial Fibrillation:

Peak digoxin body stores larger than the 8 to 12 mcg/kg required for most patients with heart failure and normal sinus rhythm have been used for control of ventricular rate in patients with atrial fibrillation. Doses of digoxin used for the treatment of chronic atrial fibrillation should be titrated to the minimum dose that achieves the desired ventricular rate control without causing undesirable side effects.

Detailed Digobal dosage information


If you overdose Digobal and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Digobal overdosage: confusion, irregular heartbeats, nausea, seizures, vomiting, extremely fast or slow heartbeats, hallucinations, tiredness, problems with vision, diarrhea, lack of appetite.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Digobal dosage information

Side effects

The most common side effects associated with Digobal are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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We report here the biochemical characterization of the human RET tyrosine kinase domain and the structure determination of the non-phosphorylated and phosphorylated forms. Mechanisms of altered plasticity after developmental traumatic brain injury. Nutritional state and the swelling-induced inhibition of proteolysis in perfused rat liver. Conventional gait labs are limited in their ability to study running gait due to their size. The architecture of the expanding wall of mung bean hypocotyl (Phaseolus aureus) and collenchyma of celery (Apium graveolens) was examined using freeze-etching without any cryoprotectant, and surface-replication of frozen-ground and air-dried specimens.

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The outcomes included the prevalence of small-bowel lesions: erosion, ulcer, angioectasia, varices, and tumor. This study provides an approach for a system-wide view of immune populations in the brain and is expected to serve as a resource for understanding brain immunity. In the Western world, our understanding of pain has evolved in concert with our understanding of the world around us. Treatment-induced changes in tumor volume, epiphyseal growth plate thickness, and microvessel density assessed by CD31 immunohistochemistry were analyzed. Mouse osteoblast-like cells grown on the three scaffolds retained their characteristic morphology. Microcrystallized cellulose was chemically modified to cellulose xanthate (MCX). Results revealed that MSM mutants remained as monomers under ambient conditions, and induced cells (breast cancer Bcap-37 cells) apoptosis even more efficiently, primarily through the caspase-dependent and Bcl-2-related pathways, than non-monomeric mutants. Dexamethasone also inhibited LPS-induced MIP-1beta release, whereas triptolide did not. In vivo tissue engineering of functional skeletal muscle by freshly isolated satellite cells glucotrol max dosage embedded in a photopolymerizable hydrogel. Ex vivo measurements in animals are used frequently in the field of nuclear medicine for the characterization of newly developed radioligands and for drug development.

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Our purpose was to estimate the rate of severe headaches occurring after injection with botulinum toxin for dermatologic indications. reesei TYR2 was purified with a three-step purification procedure, consisting of desalting by gel filtration, cation exchange chromatography and size exclusion chromatography. Indeed, it may be considered in patients experiencing difficulty tolerating treatment with continuous positive airway pressure. Manual ventilation is occasionally performed during such procedures if clinicians suspect inadequate ventilation. Isolated cardiomyocytes incorporated fluorescence-marked CpG-ODN. qRT-PCR was performed to evaluate the expression levels of SNHG15 and miR-141 in OS tissues and cells. A precise spatial and temporal alignment between episodes of cortical persistent activity and striatal Up states would allow MSN to detect specific cortical inputs embedded within a more general cortical signal.

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HIF-1 is a ubiquitous signaling molecule constantly expressed by the body, but is degraded during normoxic conditions. Can a tablet-based cancellation test identify cognitive impairment in older adults?. Five viruses were prevalent: black queen cell virus (BQCV), sacbrood virus (SBV), Israeli acute paralysis virus (IAPV) and the Lake Sinai viruses (LSV1 and LSV2), of which the latter three were detected for the first time in Australia. This histologic marker should be sought in other localized disorders of keratinization. Interventions should be designed to facilitate (and possibly require) parent involvement.

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Postnatal eyes were analyzed by histology and in situ hybridizations. Data were analyzed with the Fisher exact or chi-square test, as appropriate. The examination showed definite effects both in terms of a reduction in eating disorder-specific behavior and a statistically and clinically relevant improvement in the symptoms of depression. The role of nitric oxide in basal vasomotor tone and stimulated endothelium-dependent dilations in the coronary arteries in chronically instrumented awake dogs was studied by examining the consequences of inhibiting endogenous nitric oxide formation with the specific inhibitor of nitric oxide formation, NG-monomethyl-L-arginine (L-NMMA). We demonstrate the technique with synthesized data and compare its performances with existing methods. Influence of duration and depth of sustiva generic ether of brevinarcon narcosis on the cerebral acetylcholine content of rat.

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