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Combivent (Levosalbutamol)

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Combivent is a combination medication used to treat chronic obstructive pulmonary disease. It contains ipratropium and salbutamol. It is taken by inhalation. Common side effects include sore throat, muscle cramps, and nausea.

Other names for this medication:

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Also known as: Levosalbutamol


Ipratropium and albuterol combination is used to help control the symptoms of lung diseases, such as asthma, chronic bronchitis, and emphysema. It is also used to treat air flow blockage and prevent the worsening of chronic obstructive pulmonary disease (COPD) in patients who need another medicine.

Ipratropium and albuterol belong to the family of medicines known as bronchodilators. Bronchodilators are medicines that are breathed in through the mouth to open up the bronchial tubes (air passages) in the lungs.

This medicine is available only with your doctor's prescription.


Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Combivent Respimat is usually used 4 times per day. Follow your doctor's dosing instructions very carefully. Do not use more than 6 inhalations in a 24-hour period.

Overuse of Combivent Respimat may increase the risk of death. It is critical that you use only the prescribed dose of this medicine.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Always use the new inhaler device provided with your refill.

To use the inhaler:

You do not need to shake the inhaler before use. Uncap the mouthpiece of the inhaler. Breathe out fully. Put the mouthpiece into your mouth and close your lips. Keep your eyes closed to prevent spraying any medicine into your eyes. Breathe in slowly while pressing the dose-release button on the inhaler. Hold your breath for 10 seconds, then breathe out slowly. Close the cap until you use your inhaler again. Carefully follow all directions for cleaning your specific inhaler device once per week.

Keep track of the number of sprays you have used. Throw away the Combivent Respimat inhaler canister after 3 months or 120 sprays, whichever comes first.

To use the solution with a nebulizer:

Open the foil pouch and remove one vial. Empty the medicine into the chamber of the nebulizer. Attach the mouthpiece or face mask, then attach the drug chamber to the compressor. Sit upright in a comfortable position. Place the mouthpiece into your mouth or put on the face mask, covering your nose and mouth. Turn on the compressor. Breathe in slowly and evenly until no more mist is formed by the nebulizer and the drug chamber is empty. Clean the nebulizer after each use. Follow the cleaning directions that came with your nebulizer.

Seek medical attention if your breathing problems get worse quickly, or if you think your medications are not working as well.

To make sure this medicine is not causing harmful effects on your lungs, you may need to have chest X rays or other frequent lung function tests.

Store at room temperature away from moisture, heat, and light. Do not freeze. Keep each vial in its foil pouch until you are ready to use it.

Keep the cover on your inhaler when not in use. Keep away from open flame or high heat. The canister may explode if it gets too hot. Do not puncture or burn an empty inhaler canister.

Detailed Combivent Respimat dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Combivent Respimat can be fatal. Overdose symptoms may include chest pain, fast or pounding heartbeats, tremors, dry mouth, extreme thirst, muscle weakness or limp feeling, severe headache, pounding in your neck or ears, or feeling like you might pass out.


Store the canister at room temperature, away from heat and direct light. Do not freeze. Do not keep this medicine inside a car where it could be exposed to extreme heat or cold. Do not poke holes in the canister or throw it into a fire, even if the canister is empty.

Keep the medicine in the foil pouch until you are ready to use it. Store at room temperature, away from heat and direct light. Do not freeze.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Combivent Respimat dosage information

Side effects

The most common side effects associated with Combivent are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of Combivent® Respimat® spray in the elderly.

No information is available on the relationship of age to the effects of Combivent® in geriatric patients.

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