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Amopen (Amoxicillin)
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Amopen

Amopen is a penicillin-like (beta-lactam) antibiotic. It belongs to the most widely-used group of antibiotics available. Amopen is usually the drug of choice within the class because it is better absorbed, following oral administration, than other beta-lactam antibiotics.

Other names for this medication:
Acimox, Alfamox, Aloxyn, Amoclen, Amoksicilin, Amopen, Amoram, Amoxi, Amoxicillin, Amoxicillinum, Amoxiline, Amoxivet, Amoxypen, Amurol, Bristamox, Cipmox, Clamoxyl, Flemoxin, Flemoxon, Galenamox, Gimalxina, Hidramox, Lupimox, Moxicillin, Novamoxin, Ospamox, Penamox, Penimox, Robamox, Servamox, Sintedix, Solciclina, Stacillin, Sumox, Tolodina, Utimox, Velamox, Wymox

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Also known as: Amoxicillin

Description

Amoxicillin is used to treat bacterial infections in many different parts of the body. It is also used with other medicines (e.g., clarithromycin, lansoprazole) to treat H. pylori infection and duodenal ulcers.

Amoxicillin belongs to the group of medicines known as penicillin antibiotics. It works by killing the bacteria and preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.

Dosage

Adults: 500 mg PO every 12 hours or 250 mg PO every 8 hours for mild/moderate infections and 875 mg PO every 12 hours or 500 mg PO every 8 hours for severe infections.

Infants older than 3 months, Children, and Adolescents: 20 mg/kg/day PO in divided doses every 8 hours (Max: 250 mg/dose) or 25 mg/kg/day PO in divided doses every 12 hours (Max: 500 mg/dose) for mild to moderate infections and 40 mg/kg/day PO in divided doses every 8 hours (Max: 500 mg/dose) or 45 mg/kg/day PO in divided doses every 12 hours (Max: 875 mg/dose) for severe infections.

Neonates and Infants 3 months and younger: 30 mg/kg/day PO given in divided doses every 12 hours.

Overdose

In case of overdosage, discontinue medication, treat symptomatically, and institute supportive measures as required. If the overdosage is very recent and there is no contraindication, an attempt at emesis or other means of removal of drug from the stomach may be performed. A prospective study of 51 pediatric patients at a poison-control center suggested that overdosages of less than 250 mg/kg of Amopen are not associated with significant clinical symptoms and do not require gastric emptying.

Interstitial nephritis resulting in oliguric renal failure has been reported in a small number of patients after overdosage with Amopen.

Crystalluria, in some cases leading to renal failure, has also been reported after Amopen overdosage in adult and pediatric patients. In case of overdosage, adequate fluid intake and diuresis should be maintained to reduce the risk of Amopen crystalluria.

Renal impairment appears to be reversible with cessation of drug administration. High blood levels may occur more readily in patients with impaired renal function because of decreased renal clearance of Amopen. Amopen may be removed from circulation by hemodialysis.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

You may store the oral liquid in the refrigerator. Throw away any unused medicine after 14 days. Do not freeze.

Detailed Amopen dosage information

Side effects

The most common side effects associated with Amopen are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Children, infants, neonates, premature neonates.

Amopen has been used to treat infections in infants (3 months of age), including neonates and premature neonates. However, dosages must be modified for these age groups compared to infants (3 months of age) because of incompletely developed renal function. Safety and effectiveness of Moxatag extended-release tablets has not been established in neonates, infants, or children (12 years of age).

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