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Alsartan

Alsartan is used in adults to lower high blood pressure (hypertension), treat heart failure, improve the chance of living longer after a heart attack (myocardial infarction). Alsartan is a prescription medicine called an angiotensin receptor blocker (ARB).

Other names for this medication:
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Also known as: Valsartan

Description

Alsartan (valsartan) is an angiotensin II receptor blocker (sometimes called an ARB). Valsartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.

Alsartan is used to treat high blood pressure (hypertension) in adults and children who are at least 1 year old. Lowering blood pressure may lower your risk of a stroke or heart attack.

Alsartan is also used in adults to treat heart failure and lower your risk of needing to be hospitalized, and to lower your risk of death after a heart attack.

Dosage

Usual Adult Dose for Congestive Heart Failure:

Initial dose: 40 mg orally twice a day Maintenance dose: 80 to 160 mg twice a day. The dose should be increased to the highest dose tolerated by the patient.

Usual Adult Dose for Hypertension:

Initial dose: 80 to 160 mg orally once a day. Maintenance dose: 80 to 320 mg orally once a day

Usual Adult Dose for Myocardial Infarction:

Initial dose: 20 mg orally twice a day Maintenance dose: The initial dosage may be titrated upward within 7 days to 40 mg twice daily, with subsequent titrations to a target maintenance dose of 160 mg twice a day as tolerated by the patient. If symptomatic hypotension or renal dysfunction occurs, consideration should be given to a dosage reduction. Comment: Valsartan may be initiated as early as 12 hours after a myocardial infarction, and may be given with other standard postmyocardial infarction treatment, including thrombolytics, aspirin, beta blockers, and statins.

Usual Pediatric Dose for Hypertension:

6 to 16 years: Initial dose: 1.3 mg/kg once a day (up to 40 mg) Maintenance dose: up to 2.7 mg/kg (up to 160 mg) once a day titrated according to patient response Comments: If the calculated dosage does not correspond to the available tablet strengths, or if children are unable to swallow tablets, the use of a suspension (which can be prepared from the tablets) is recommended. The valsartan dose may need to be increased if the suspension is replaced by a tablet. No data are available in pediatric patients either undergoing dialysis or with a glomerular filtration rate less than 30 mL/min.

Detailed Alsartan dosage information

Overdose

If you overdose Alsartan and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Alsartan overdosage: fainting, abnormal heartbeats, lightheadedness.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep your medicine container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alsartan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use this medicine if you are allergic to valsartan or hydrochlorothiazide, or if you have:

decreased urination or are unable to urinate; or an allergy to sulfa drugs.

If you have diabetes, do not use Alsartan HCT together with any medication that contains aliskiren (a blood pressure medicine).

You may also need to avoid taking Alsartan HCT with aliskiren if you have kidney disease.

Tell your doctor if you have ever had:

an electrolyte imbalance (such as low levels of potassium or magnesium, or high levels of calcium in your blood); liver disease; kidney disease; gallstones; lupus; congestive heart failure; gout, or high levels of uric acid in your blood; asthma or allergies; high cholesterol or triglyceride levels; an allergy to penicillin; glaucoma; or if you are on a low-salt diet.

Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Valsartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

You should not breastfeed while using this medicine.

Alsartan HCT is not approved for use by anyone younger than 18 years old.

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All five patients who, while still in the chronic phase, had a major 3.1-kb hypermethylated calcitonin gene fragment, accelerated within 2 to 27 months. Reply to Westaway et al.: Mandibular misrepresentations fail to support the invalid species Homo floresiensis. Due to inadequate reporting and evaluation, the mechanisms for achieving effective recruitment and engagement in sport, particularly in hard-to-reach groups, are still unclear. NPC1-YFP produced in astrocytes or in cells of visceral tissue did not. We enrolled adult patients with acute, purulent skin and soft-tissue infections presenting to 11 university-affiliated emergency departments during the month of August 2004. Calculated values of the excess partial molar volumes of water and 1-propanol and the excess molar volume of the mixture are in good agreement with experimental values. Besides detector concepts and system integration the challenges and proposed solutions for attenuation correction and the potential for motion correction and resolution recovery are also discussed in this topical review. At this time point, inflamed eyes were examined for their capacity to afford immune privilege to injected allogeneic tumor cells, and to promote anterior chamber-associated immune deviation (ACAID) to antigens injected locally. Recent advances in cancer molecular biology have resulted in parallel and unprecedented progress in the development of targeted cancer therapy. The low price of such equipment favourably compares with the benefits of its use.

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