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Alprocontin (Alprazolam)

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Alprocontin is commonly used to treat anxiety and panic disorders. It falls into a category of medications called benzodiazepines. They are known to affect the central nervous system components and produce a calming effect, thus decreasing brain activity.

Other names for this medication:
Aleez, Allam, Alltop, Alpramax, Alprasert, Alprazan, Alprogard, Altalin, Alwe, Alzoax, Alzolite, Ambulax, Anilam, Berest, Cardilax, Emlol, Enxolam, Exprex, Flunix, Indolam, Mebrin, Plaxid, Proprazolam, Rescalm, Tenolam, Zeprax, Zolorest, Zolran

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Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alprocontin. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Alprocontin XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alprocontin dosage information

Side effects

The most common side effects associated with Alprocontin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Regression and mixed effects repeated measures analyses revealed that trauma exposure did not moderate changes in symptoms and functioning over time for women in UC versus IPT-B. Introduction of the technic of external arteriovenous shunt and subcutaneous arteriovenous fistula for performing hemodialysis in children. A secondary or recurrent uveitis was induced by intravenous injection of the specific soluble antigen several months after the cessation of primary inflammation. The bound glycoproteins were detected by time-resolved fluorometry using europium-labeled antibodies. Conservative management of high grade renal injuries is common in children. Data regarding catheter ablation of anteroseptal accessory pathways through the aortic cusps are limited.

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Bronchoscopic study on aetiology of chronic cough in HIV-infected adults with negative sputum smears for Mycobacterium tuberculosis at Kenyatta National Hospital, Nairobi. Isolation and characterization of novel sulfate-reducing bacterium capable of anaerobic degradation of p-xylene. Interest of immunohistochemistry for the diagnosis of benign hepatocellular tumors. Side effects have been low, anemia related to ribavirin being the main one. Atenolol blocked the adrenergic relaxation, suggesting a predominance of beta 1-adrenoceptors.

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Center-specific donor risk factors for pancreas graft survival after simultaneous pancreas-kidney transplantation were identified in this study, the importance of which need to be better defined. Fetuin-A is a mineral carrier protein: small angle neutron scattering provides new insight on Fetuin-A controlled calcification inhibition. Advanced practice nurses can refine the management of heart failure. In this article, we discuss the rationale for and application of small intestinal submucosa (SIS) in lower urinary tract tissue engineering, with emphasis on the use of SIS as a suitable and biologically compatible sling material. Choice of rootstock resulted in differential response to drought stress. However, there is weak epidemiological support for WBV-induced disorders of organ systems other than the lower back. Pachycladins are eunicellin-based diterpenoids isolated from the soft coral Cladiella pachycladous species.

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Differential family environments of bulimics and victims of childhood sexual abuse: achievement orientation. To study the atonic elements combined or uncombined with epileptic spasms in infantile spasms. There is, however, much promise to support further study of this ventilatory modality. The venom compositions of sixteen Parabuthus species, occurring in southern Africa, were characterized using representative peaks in the molecular mass range of 6400-8400 Da. Small cell neuroendocrine carcinoma of the cervix: analysis of the prognosis and role of radiation therapy for 43 cases.

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What I like about you: the association between adolescent attachment security and emotional behavior in a relationship promoting context. Nuclear factor kappaB (NF-kappaB) activation was also detected in THP-1 cells transiently transfected with an NF-kappaB-driven luciferase reporter gene. Patients were block randomized pre-operatively to receive placebo or donepezil 5 mg immediately following surgery and every 24 h thereafter for a further three days. Phase 1 clinical study of the acute and subacute safety and proof-of-concept efficacy of carbohydrate-derived fulvic acid. This review examines the indications for chest wall reconstruction and describes techniques for establishment of chest wall rigidity and soft tissue coverage.

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International coordination is needed now that research funds are scarce. At the same time, new highly conformal irradiation modalities may significantly improve the tolerance to radiation. The selective toxicity was often shown by experiments with in vitro screening test in human cancer cell (JTC-26) and human normal embryonic cell (HE-1) on the crude extract of crude drugs. Treatment with meclofenamic acid supported the establishment of pregnancy in recipient mares that ovulated before the donors. Elderly subjects were susceptible to the toxicity of high-dosage rhubarb, which drove rigorous consideration on rational use of rhubarb to aged people. The changes in TnTf composition occurred in parallel with previously demonstrated transitions within the pattern of the fast myosin heavy chains in the same muscles. A hidden Markov model to predict early mastitis from test-day somatic cell scores.

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Here we report a Brucella strain isolated from multiple lymph nodes of one bottlenose dolphin (Tursiops truncatus) during routine examination of dolphin carcasses found in the Croatian part of the northern Adriatic Sea during the summer of 2015. Functional imaging of the retinal microvasculature by scanning laser Doppler flowmetry. Urinary tract infection and surgical disorders of the lower urinary tract. For such purpose, in this study, we developed a technique of how to obtain small nanopores in silicon nitride films using a focused-ion-beam (FIB) system. Recent studies provide new insights into these important questions by showing the contribution of hair follicle SC to the sebaceous lineage and the importance of chromatin modifications and micro-RNAs (miRs) in regulating epidermal SCs renewal and differentiation. However, newer, 3-dimensional mapping technologies offer multiple options for minimizing fluoroscopy use.

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Aspects of pneumococcal infection including bacterial virulence, host response and vaccination. These data suggest that MYCN expression is a common feature of rhabdomyosarcoma, independent of gene amplification and without a clear relationship with specific histological and clinical features. Our systematic review of the literature identified some evidence of interactions, most notably for a common variant in the PPAR-gamma gene which appears to interact with the nature of dietary fat intake. Not only are they the structural units of membranes and vesicles, but both classes of molecules also participate actively in membrane transport processes. The staging and treatment of ovarian cancer is reviewed with special attention to developments during the last decade. Western blot analysis revealed the efficient expression of both the SIP and IgA molecules. One therapeutic strategy to treat diseases with increased cellular proliferation rates, most obviously cancer, has been to identify compounds which lower cellular polyamine levels. Links between obesity and cardiovascular diseases are now well established.

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The sensitivity of the non-ophthalmologists varied between 100 per cent and 88 per cent, depending on the standard (diagnosis of one ophthalmologist or consensus between two ophthalmologists). Multidimensional assessment of spirituality/religion in patients with HIV: conceptual framework and empirical refinement. The margin between the tumor and neurovascular structure was evaluated, and an additional procedure, such as pasteurization, alcohol soaking or distilled water soaking, was performed, according to the safety of the surgical margin. Here we propose a new surgical classification that may help to decide the most suitable approach to the PA according to the location and extension of the lesion. Theoretical bases and applications of new therapeutic tables for the treatment of diving accidents. However, the cytoarchitecture of one of these subdivisions, the pars lateralis (SNl), has not been previously examined in detail at the light and electron microscopic levels in any species. An assessment of the effect of user fee policy reform on facility-based deliveries in rural Zambia.

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This exploratory qualitative study combined non-participant observation and in-depth interviews. Thermal Alternating Polymer Nanocomposite (TAPNC) Coating Designed to Prevent Aerodynamic Insect Fouling. This represents a novel example of spontaneous colorectal neoplasia in rodents that is not based on germline modification of one or more already-identified cancer-related genes. The National Survey revealed a changing profile of TB in Japan and suggested a need to review and revitalise the TB control programme. However, comparing the incisal, middle and cervical thirds, no statistically significant differences were observed. Parvovirus B19-induced pure red cell aplasia in a liver transplant recipient. Patients were evaluated for compliance and theophylline toxicity after receiving Theo-Dur for one week. NADPH levels and basal activity of the PC increased at 42 degrees C. Platelet-rich plasma (PRP) therapy is an emerging technology that aims to improve the process of tissue repair through local delivery of autologous bioactive agents to influence critical physiological mechanisms such as inflammation, angiogenesis, or extracellular matrix synthesis. Topical application of TAM significantly induced a number of DNA-adducts in mouse skin in a dose- and time-dependent manner.

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Gbetagamma release and tyrosine kinase receptor transactivation. What Is the Optimal Target Convective Volume in On-Line Hemodiafiltration Therapy?. To investigate the changes of nuclear factor kappa B (NF-kappaB), cyclooxygenase-2 (COX-2) and matrix metalloproteinase-9 (MMP-9) in human term myometrium before and during term labor. Long-term results of organ transplantation are still limited by serious side effects of immunosuppressive drugs. Canine PYY(1-36) has the identical sequence as porcine and rat PYY but differs from human PYY at position 3, with Ala instead of Ile, and position 18, with Ser instead of Asn. The results of long-term treatment of coxarthrosis with Indomethacin. In this study, cancer cells are targeted by using positively-charged, fluorescent, superparamagnetic Fe3O4-composite nanoparticles. Upon exome sequencing, point mutations were identified in seven candidate genes (Sspo, Dguok, Hoxaas2, Clstn3, Atm, Tipin and Mapk6).

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It was also established that is more expressed for the facial height and bigonial distance. Data collected in this study suggest that: (1) ALCAP ceramic capsules are capable of delivering D and DHT continuously for 12 months, (2) the amount of D and DHT released by ALCAP capsules was sufficient to suppress spermatogenesis and induce azoospermia in rats. Extending research on parenting in mothers diagnosed with BPD: commentary on Stepp et al. The preparations from diphenylamine-grown cells are also more active in system I mediated electron transport from reduced dichloroindophenol to oxygen or methyl viologen. Elastin particles (diameter smaller than 0.1 mm) prepared by extraction of bovine nuchal ligament with alkali had no effect on wet weight and dry weight of granulation tissue formed in the wound within 6 days. Does a selective 5-hydroxytryptamine antagonist (ICI is it ok to take zyrtec while drinking alcohol 169, 369) lower blood pressure in hypertensive patients?.

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Cytotaxonomy of the Ciconiiformes (Aves), with karyotypes of eight species new to cytology. Fumonisin B1 was detected in all 24 samples tested at levels of between 68-6,555 (micrograms/kg), and aflatoxin was detected in 2 samples heavily contaminated with Aspergillus flavus. Neocartilage formation has not heretofore been described in this model. By using reporter gene assay, we showed that the loss of the central region does not influence the TEL/AML1-mediated transcriptional repression. Patients with Cri Du Chat syndrome have clinical characteristics that are very important for their anesthetic management, being the responsibility of the anesthesiologist to consider carefully the structural particularities of each patient. The results show that members of both groups are little informed about genetics. This article is part of a Special Issue entitled: 11th European Symposium on Calcium. The animals were sacrificed 7d, 14d, and 21-28d after treatment. The LDR Do value of the neo-r KM 104 cocultivated for 24 hr before, and during gamma irradiation with excess of parent KM 101, was significantly higher, compared to the neo-r cells irradiated alone. A cross-sectional survey of a community sample of participants aged 65 yr and older registered with 20 family practices in the United Kingdom.

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Intraoperative tissue fluorescence using 5-aminolevolinic acid (5-ALA) is more sensitive than contrast MRI or amino acid positron emission tomography ((18)F-FET PET) in glioblastoma surgery. The modern hospital epidemiologist has broad perspectives and influence across clinical departmental lines. Isoproterenol, which stimulated acid secretion in our experiments, induced relaxation of the stomach in a dose-dependent manner. Local rearrangements are favored over distal and interchromosomal rearrangements. Activation of murine spleen cells in vitro by co-cultivation with X63-m-IL-2 cells gave rise to lymphokine-activated killer (LAK) cell populations cytotoxic for the X63-Ag8.653 plasmocytoma and MC14 sarcoma. ScFv-mel-FLAG bound specifically to HMy2 cells in direct binding assays and this binding was completely inhibited in the presence of an excess of soluble antigen. The results of these experiments suggest a two-step mechanism in prolonging luteal function during pregnancy which involves two different substances. Consequently, alterations in histamine-related factors could be an important part in the cause of multiple rare/orphan diseases. Plasmodium yoelii uses the murine Duffy antigen receptor for chemokines as a receptor for normocyte invasion and an alternative receptor for reticulocyte invasion. Molecular and histological data suggested a possible transdifferentiation of brown into white adipocytes, but this hypothesis has now been challenged by the characterization of distinct precursor cells for brown and white adipocytes in mice.

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The use of dental sealants has remained relatively low in the U.S. The presence of halothane might have contributed to the arrythmia. Monte Carlo methods and clinical constraints were used to design the optimal cone applicator. Our results suggest that cell survival is contingent upon a diverse array of signals in sea urchins, more comparable in complexity to vertebrates than to arthropods or nematodes, but also with unique features that may relate to specific requirements imposed by the biphasic life cycle and/or immunological idiosyncrasies of this organism. The desert gerbil Psammomys obesus, an established model of type 2 diabetes (T2D), has previously been shown to lack pancreatic and duodenal homeobox gene 1 (Pdx-1) expression. Adoption of short-term mechanical circulatory support as a viable rescue effort for patients with refractory cardiogenic shock. The effectiveness of preoperative immunonutrition has not been evaluated in a community setting. On the other hand, the second diastereoisomer 34 would be transformed to 2-epi-congener.

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Analysis of risk factors influencing outcome in children with myelodysplastic syndrome after unrelated cord blood transplantation. To determine whether endogenous opioids contribute to the pruritus of cholestasis by studying the effect of the opiate antagonist naloxone on the perception of pruritus and on scratching activity in patients with this form of pruritus. Characterization and cloning of MwoI (GCN7GC), a new type-II restriction-modification system from Methanobacterium wolfei. It was assumed that this type of aggregation involves reversible changes of the surface structure of RBC. It is reported here that the mitogenic response of murine lymphocytes is altered in the presence of tricyclic antidepressants at concentrations of 10(-5) M or greater. In this study, we introduced and evaluated a simple method for UCF correction after tubularized incised plate (TIP) repair.

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To evaluate the safety, tolerability, and efficacy of varying doses of recombinant human interleukin-6 (rhIL-6) after chemotherapy. Reappraisal was, however, particularly consequential for young women who experienced higher levels of negative affect compared with men fenofibrate 145 mg tab of the same age and older aged women. Diet and chemotherapy offer the hope of slowing stone growth and/or recurrence in patients with chronic urease-producing bacteriuria. Histologically, there was extensive necrosis and nonsuppurative inflammation of the cerebral gray and white matter, overlying meninges, and adjacent thalamus and hippocampus. Adrenal medullary allografts, as well as other monoaminergic tissues, have been demonstrated in our laboratory to increase antidepressive activity when transplanted into the frontal neocortex of rats. It is inexpensive, easily available and well tolerated medicine.

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It is not necessary to distinguish between stem and terminal segments or to specify daughter branch ratios or dendritic taper. We studied CB1 and endocannabinoid enzymes (EE), Adiponectin (Ad), and Insulin (SI) in lean and obese pre-pubertal (PP) children. Advances in the treatment of medulloblastoma have largely been attributed to the introduction of chemotherapy, although Phase III trials have shown advantages for chemotherapy only in subgroups. The no-observed-effect level (NOEL) established from these studies was 2.5 ml VOT/l drinking water (approximately equivalent to an daily intake of 0.4 mg/kg body weight). Elevated sulfated acid polysaccharide levels in urine and postmortem tissues. However, an array detector scheme for confocal microscopes solves this problem and is therefore of interest in restoring the data of array detectors to its original image. Quadriceps muscle biopsy disclosed diffuse vascular calcific deposits on medium- and small-sized vessels, characteristic of CUA. The IR bands are found to be characteristic of the degree of adsorption/confinement of the liquid water. Magnetic resonance spectroscopy (MRS) is an alternative approach that holds great promise for aiding target definition for radiotherapy treatment planning, and for evaluation of response and recurrence. Additionally hyperfibrinolysis, hypothermia, acidosis and metabolic changes affect the coagulation system.

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In this study, we investigated the association of BMI-related SNPs with psychiatric diseases and one of their endophenotypes, memory performance, in a Japanese population. Out of the investigated genes, is 50 mg of tramadol safe the richness of the genes related to carbon cycling was significantly higher in fields abandoned for longer time. Giant cavernomas do not differ from average-sized cavernomas in clinical, surgical or histopathological presentation but may differ radiologically. Effect of different mixing methods on the physical properties of Portland cement. Combined immunosuppressive and anticoagulant treatment in children with glomerulonephritis and declining renal function. However, basal FN is progressively removed in confluent cultures and substituted by non-fibrillar FN deposits at lateral cell domains in regions of cell-cell contacts. It is stressed that conventional diversity formulae cannot be informative on community structure, but there is a solution. It supports the need for using ultrasound-guided techniques for IJV cannulation following LMA insertion in spontaneously breathing children. Lung diffusing capacity for carbon monoxide (DLCO) was reduced in the majority of patients along the three time periods after radiation, whereas the forced expiratory volume in 1 s per unit of vital capacity (FEV1/VC) showed an increase and decrease after radiation in a similar percentage of patients. Treatment of ssdRGC-5 cells with B/G increased intracellular ROS and induced apoptosis (not necrosis) with increasing caspase-3 activity.

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Ipz-2 Langmuir films have been transferred onto solid substrates, and Atomic Force Microscopy (AFM) images of the Langmuir-Blodgett films have shown that large columnar structures hundreds of nm in diameter are formed on top of the initial monolayer, in contrast with well-defined trilayer LB films obtained for Ipz. This condition is uncommon, with only 30 female congenital external genital cysts previously reported in the English literature. Ellagic acid, epigallocatechin gallate and vitamin C demonstrated partial protection. The cooperative enzyme reaction rates predicted by the bi-substrate Hill equation and the can you take claritin while breastfeeding bi-substrate Monod-Wyman-Changeux (MWC) equation when allosterically inhibited are compared in silico. Detection and characterization of circulating antigens in acute experimental infections of mice with four different strains of Toxoplasma gondii. It is also underlined that in case of an urographically silent kidney the attitude should be conservative and the treatment of the malignant infiltrative tumors of urinary bladder should be multimodal. The arbuscular mycorrhizal community of 48 MOTUs was exhaustively sampled and followed log-normal distribution.

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