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Alprine (Alprazolam)

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Alprine is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alprine, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alprine is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alfix, Alparazole, Alpkair, Alprax, Altrex, Alzep, Alzorix, Alzoset, Andep, Anzal, Azolam, Calmef, Depoxit, Depten, Esteem, Luzarn, Maxorest, Pifzot, Plaxid, Proprazolam, Prosanti, Prozam, Selamb, Serxanti, Silam, Somaspas, Somnia, Sowel, Tenzorid, Wycalm, Zallpam, Zenax, Zolin, Zoltweet, Zopain, Zopral, Zotin

Similar Products:
Sinequan, Danocrine, Naprosyn, Avodart, Viramune, Compazine, Soma, Abilify, Theolair, Dilantin, Imprax, Ejectil, Risperiv, Lexapro, Probenecide, Atcet, Primodil, Mycomax, Mecospan,

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


Take this medication by mouth as directed by your doctor. Dosage is based on your medical condition, age, and response to treatment. Your dose may be gradually increased until the drug starts working well. Follow your doctor's instructions closely to reduce the risk of side effects.This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. In such cases, withdrawal symptoms (such as seizures) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Report any withdrawal reactions immediately.Along with its benefits, this medication may rarely cause abnormal drug-seeking behavior (addiction). This risk may be increased if you have abused alcohol or drugs in the past. Take this medication exactly as prescribed to lessen the risk of addiction.When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well.Tell your doctor if your condition persists or worsens.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alprine XR dosage information

Side effects

The most common side effects associated with Alprine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Before taking Alprine, tell your doctor or pharmacist if you are allergic to it; or to other benzodiazepines (such as diazepam, lorazepam); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: severe lung/breathing problems (such as COPD, sleep apnea), liver disease, kidney disease, drug or alcohol abuse, glaucoma.This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).Older adults may be more sensitive to the side effects of this drug, especially loss of coordination and drowsiness. These side effects can increase the risk of falling Alprine is not recommended for use during pregnancy due to the potential for harm to an unborn baby. Consult your doctor for more details.This drug passes into breast milk and may have undesirable effects on a nursing infant. Therefore, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

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The In deposition rate is varied from 0.2 ML/s to 0.4, 0.8 and 1.6 ML/s. The aim of this study was to determine the prevalence of sustained IOP elevation following intravitreal bevacizumab injections for neovascular AMD and identify possible risk factors for the development of increased IOP. By contrast, collagen V-mediated autoimmunity was increased in the subgroup of smokers and may potentially contribute to the pathogenesis of COPD. The data presented in this paper indicate that A(1-7) reduces the consequences of critical radiation exposure and can be initiated well after initial exposure with maximal effects on early responding hematopoietic progenitors when treatment is initiated 2 days after exposure and 5 days after exposure for the later responding progenitors and reduced thrombocytopenia. The results of this model indicate that N saturation reduced global NPP (Net Primary Productivity) and NEP (Net Ecosystem Productivity) by 0.26 and 0.03 Pg C yr-1, respectively. Transvaginal ultrasonographic detection of primary ovarian pregnancy with laparoscopic removal: a case report. With expanding indications for androgen deprivation therapy for the treatment of prostate cancer, it is imperative that health care providers be cognizant of the possible adverse effects of therapy, as well as their prevention and treatment. Injury-induced cell proliferation was significantly lower in Smad3 null mice around the lesion. We hypothesize that a surgeon will experience greater ergonomic stress when performing laparoscopic surgery.

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Selective Adsorption and Separation through Molecular Filtration by Hyperbranched Poly(ether amine)/Carbon Nanotube Ultrathin Membranes. The correlation of the degree of thermoresistance of the cells of definitive tissues and oocytes in different individual frogs. Leptin, an important adipose hormone that regulates energy balance and appetite, exerts its physiological functions via leptin receptors. At surgery, the diagnosis should be considered if thick, tenacious allergic mucin is encountered in the atopic patient with nasal polyps. Mother-to-child transmission of the human immunodeficiency virus. As there are important implications for anesthesiologists and emergency medicine physicians, a review was undertaken to document the scope of the problem of ACEI-induced angioedema.. The under- and over-diagnosis of mania in children and adolescents.

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To check whether rumen bacteria can synthesize alkanes from carbon structures other than waxes (e.g. Photosensitizing activity of advanced glycation endproducts on tryptophan, glucose 6-phosphate dehydrogenase, human serum albumin and ascorbic acid evaluated at low oxygen pressure. P53 is necessary for the apoptotic response mediated by a transient increase of Ras activity. Aggressive perioperative management, with progressive preoperative pneumoperitoneum, is a worthy method of repairing massive ventral hernias with associated loss of domain in morbidly obese patients. Binding capacity of estrogens were found to be similar to that of the normal mature placenta.

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Two-electron distribution functions and short-range electron correlations of atoms and molecules by first principles T-matrix calculations. F-actin staining with fluorescein isothiocyanate-phalloidin showed that both dbcAMP- and latrunculin B-treated cells displayed a much lower fluorescence than control cells, with only a few pale plaques. Further reductions in mortality will require improved diagnostic and novel therapeutic approaches for this group of aggressive opportunistic molds. Biosorption of Food Green 3 by a novel green generation composite biosorbent from aqueous environment. Fifty Cryptosporidium-positive specimens collected between 2001 and 2004 from pediatric patients in Kolkata, India were analyzed for parasite genetic structure using multilocus sequence typing (MLST). Ted is a 38 year old service technician for a large chemical company servicing cooling towers at a car manufacturing plant. Little change was noted in the rotational freedom between an implant and its abutment, even though the insertion torque was far beyond clinical application. Grains have always been the major source of mycotoxins in the diet of man and his domestic animals.

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The effect of prior breast biopsy method and concurrent definitive breast procedure on success and accuracy of sentinel lymph node biopsy. The effects of injections of either bombesin (BBS) or cholecystokinin octapeptide (CCK-8) on patterns of food intake of macronutrients were examined in adult male rats, and compared to the effects following saline injections. Between October 1993 and January 1994, 22 primary unilateral hernia, and two bilateral repairs were undertaken. Due to short and variable windows of detection, the chances that an active substance user will be detected during the 6-month waiting period depend on the testing method and the drug. The transcription factor EGR-1 (early growth response gene-1) plays an important role in cell growth, differentiation and development. Improved strategy for the management of this combination of metabolic disorders is needed. More double-blind randomised placebo-controlled trials into the long-term efficacy and safety of second generation antipsychotics are needed. On the other hand, fosfomycin protected the proximal tubular lysosomes from the injury of aminoglycoside, as evidenced a) in vivo by suppression of myeloid body formation and protection of lysosomal membrane integrity of the rats treated with dibekacin, and b) in vitro by dose-dependent protection of the lysosomal membrane integrity of the kidney cells.

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Quality evaluation of commercially available male condoms in Rio de Janeiro, Brazil, 2009-2011. One epidermolytic EB case showed scattered fragments of keratinocytes inside the blister. Data supporting physical activity guidelines to prevent long-term weight gain are sparse, particularly during the period when the highest risk of weight gain occurs. There is increasingly awareness for the occurrence of docetaxel and/or docetaxel-drug-induced liver injury (DILI), although the underlying mechanism of occurrence and its risk factors remain unclear. Moreover, no significant variations in testosterone, dehydroepiandrosterone sulfate, or sex hormone-binding globulin concentrations were observed after either treatment. After sequencing, two novel SLC26A4 mutations (c.65-66insT in exon 2 and c.2106delG in exon 19) were revealed in the two studied families. Opinion article: cytomegalovirus is a risk factor in atherogenesis.

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The findings demonstrate that the respondents regard the nuclear power plant as an extremely high-risk facility, causing them to oppose the SNPP and reject the compensation payment to accept its continuing operation. Management of symptoms in children with autism spectrum disorders: a comprehensive review of pharmacologic and complementary-alternative medicine treatments. If an immaculate colon preparation must be performed and if the costs reflect standard abdominal and pelvic CT rather than a special reduced cost for VC, then it is doubtful that there will be any significant impact from this technology. Steady state pharmacokinetics of the new antitussive compound vadocaine hydrochloride. As poxviruses are large, complex viruses, they present technological challenges for simple recombinant vaccine development where a multicomponent mixtures of vaccine antigens are likely important in protection. The developmental aspect of genetics is suggested to consider in future research strategy, interpretation of the results, understanding the role of genes and environment in health and disease, and construction of health service delivery system in genomic medicine. Robust spin-orbit torque and spin-galvanic effect at the Fe/GaAs (001) interface at room temperature. These results demonstrate that spectro-ptychography offers a superior means of characterizing the chemical and magnetic properties of MTB at the individual magnetosome level.

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Testing response-stimulus equivalence relations using differential responses as a sample. Effect of amnioinfusion on the incidence of postpartum endometritis in patients undergoing cesarean delivery. A high dose of niridazole administered intraperitoneally (i.p.) to male rats over a period of 9 weeks induced alterations in the concentrations and activities of some important testicular constituents and enzymes, respectively. Assessing self-reported measures of voice disability in motrin dosage chart children tracheoesophageal speakers. Prevalence and types of crystal deposits in the menisci of two hundred fifteen cadavera. Endogenous hormones resulting from ovarian secretion have effects on the endometrium independent of, and in combination with, exogenous progestogens. Work done by the Select Committee of Experts on Histocompatibility: 1978-1981. Tumour necrosis was also markedly observed in the tumour tissues after RANTES gene transfer, which was attributed to reduced expression of vascular endothelial growth factor (VEGF) and matrix metalloproteinase (MMP-2). Would a Federal Judicial Science Board improve toxic tort litigation?. Thermofiltration in hypercholesterolemia treatment: analysis of removal and posttreatment cholesterol recovery.

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Imaging modalities with plain films, ultrasound, computed tomography and angiograms are presented. With regard to fungal succession, Cladosporium cladosporioides and Eurotium brefeldianum occurred only in the late stages of dung decomposition whereas Talaromyces helicus, Cercophora coprophila and Sporormiella minima occurred in all the stages. The N-N distances are in the range 1.169 (8)-1.190 (5) A, typical for the azide group. A flexible strategy for the preparation of nanostructures of gold nanoparticles (AuNPs) through DNA directed assembly has been proposed. High incidence of thyroid dysfunction despite prophylaxis with potassium iodide during (131)I-meta-iodobenzylguanidine treatment in children with neuroblastoma. E2 protected BAEC from apoptosis induced by TNF-alpha in a concentration-dependent manner.

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Few studies have been conducted to elucidate the psychological distress of cancer outpatients being treated with chemotherapy. Among the Japanese children with hemophagocytic lymphohistiocytosis (HLH) registered at our laboratory, those with more than one of the following findings were eligible for study entry under a diagnosis of FHL: positive for known genetic mutations, a family history of HLH, and impaired CTL-mediated cytotoxicity. LPV/r exposure during late pregnancy was lower compared to postpartum and compared to non-pregnant historical controls. Functional status measurement and the assessment of health status are reaching their maturity as technical disciplines. To date, the most consistent association is between IDDM and markers of the insulin gene locus. A series of studies on this subject has been completed and some of the results have been reported earlier. Use of an ex vivo rat lung model in which the above variables were individually varied permitted a direct approach for these studies.

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Combined amyloidosis of the AA and AB type following chronic hemodialysis. We characterized robot-assisted laparoscopic radical prostatectomy outcome by hospital volume using the Nationwide Inpatient Sample during the last quarter of 2008. Uveitis recurrence rate, initial treatment response, treatment response, and medication use at 6 months, 1 year, and last visit. Cloudy lenses and issues: a pedigree of unoperated congenital cataracts. The proportion of births outside marriage increased by a further 1 per cent between 1992 and 1993, to reach 32.2 per cent. Medication information websites vary widely in quality and content. Hypoalbuminaemia is associated with increased risk of cardiovascular disease. Software for dynamic analysis of tracer-based metabolomic data: estimation of metabolic fluxes and their statistical diovan 320 mg analysis. The mechanical integrity of the cages remains intact for at least 6 months.

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