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Alpostin (Alprostadil)

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Alpostin is used to treat erectile dysfunction (impotence) and to help diagnose certain causes of this disorder. Alpostin is also used to improve blood flow in newborn babies with heart problems. This medication guide addresses only the adult male use of Alpostin in erectile disorders.

Other names for this medication:
Alpostin, Caverject, Edex, Muse, Prostin, Vitaros

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Also known as: Alprostadil


Alpostin urethral suppository is used to treat men who have erectile dysfunction (also called sexual impotence). It belongs to a group of medicines called vasodilators that can increase blood flow by expanding blood vessels. Alpostin causes an erection because it increases the blood flow to the penis.

Alpostin should not be used as a sexual aid by men who do not have erectile dysfunction. If the medicine is not used properly, permanent damage to the penis and loss of the ability to have erections could result.

Alpostin is available only with your doctor's prescription.


Read the Patient Information Leaflet provided by your pharmacist before you start using Alpostin and each time you get a refill. Learn all usage instructions in the product package. If any of the information is unclear, consult your doctor or pharmacist. This medication is used by inserting the suppository into the penis as directed by your doctor. Dosage is based on your medical condition and response to therapy. This medication should usually work within 5-10 minutes to produce an erection that lasts for about 30-60 minutes. The manufacturer recommends that you use no more than 2 doses in a 24-hour period. Inform your doctor if your condition persists or worsens (e. g. , the drug does not produce an erection or it becomes more difficult to get an erection).


If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: fainting, painful/prolonged erection.


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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

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