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Alfazosin (Doxazosin)
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Alfazosin

Alfazosin belongs to a class of drugs known as alpha blockers. Alfazosin is used in men to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia-BPH). It does not shrink the prostate, but it works by relaxing the muscles in the prostate and part of the bladder.

Other names for this medication:
Alfazosin, Doxacard, Doxapress, Doxazosin, Duracard, Duraten

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Also known as: Doxazosin

Description

Alfazosin (doxazosin) is an alpha-adrenergic (AL-fa ad-ren-ER-jik) blockers. Doxazosin relaxes your veins and arteries so that blood can more easily pass through them. It also relaxes the muscles in the prostate and bladder neck, making it easier to urinate.

Alfazosin is used to treat hypertension (high blood pressure), or to improve urination in men with benign prostatic hyperplasia (enlarged prostate).

Alfazosin XL, the extended-release form of this medicine, is used to treat benign prostatic hyperplasia and should not be used to treat hypertension.

Dosage

Usual Adult Dose for Hypertension:

Initial dose: 1 mg orally once a day. Maintenance dose: 1 to 16 mg orally once a day.

Usual Adult Dose for Benign Prostatic Hyperplasia:

Initial dose: Immediate-release: 1 mg orally once a day. Extended-release: 4 mg orally once a day with breakfast Maintenance dose: Immediate-release: 1 to 8 mg orally once a day. Extended-release: 4 to 8 mg orally once a day with breakfast. Depending on the patient's symptomatic response and tolerability, the dose may be increased to 8 mg (the maximum recommended dose). The recommended titration interval is 3 to 4 weeks. If switching from immediate-release to extended-release tablets, therapy should be initiated with the lowest dose (4 mg once daily). Prior to starting therapy with Alfazosin extended-release tablets, the final evening dose of immediate-release tablets should not be taken. If Alfazosin extended-release tablets are discontinued for several days, therapy should be restarted using the 4 mg once daily dose.

Usual Geriatric Dose for Hypertension:

Initial dose: 0.5 mg orally once a day.

Detailed Alfazosin dosage information

Overdose

If you overdose Alfazosin and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alfazosin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Alfazosin if you are allergic to doxazosin or similar medicines such as alfuzosin (Uroxatral), prazosin (Minipress), silodosin (Rapaflo), tamsulosin (Flomax), or terazosin (Hytrin).

To make sure Alfazosin is safe for you, tell your doctor if you have:

a blockage in your digestive tract (stomach or intestines); severe constipation; liver disease; or low blood pressure.

Alfazosin can affect your pupils during cataract surgery. Tell your eye surgeon ahead of time that you are using this medication. Do not stop using Alfazosin before surgery unless your surgeon tells you to.

It is not known whether doxazosin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether doxazosin passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using Alfazosin.

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