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Acuzole (Metronidazole)

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Acuzole belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

Other names for this medication:
Amevan, Amobin, Biatron, Colpofilin, Cresac, Dirozyl, Entizol, Fladex, Fladystin, Flagenase, Flagystatine, Ginerella, Kilpro, Klion, Klont, Litagyl, Medamet, Metral, Metris, Metrodal, Metroderme, Metrofusin, Metrolotion, Metrolyl, Metrosil, Metrozol, Micogyl, Negazole, Nidagyl, Nipazol, Nizole, Otrozol, Protozol, Robaz, Rosaced, Rosazol, Rovamet, Rozamet, Supplin, Tolbin, Trichazole, Trichex, Trichopol, Tricofin, Trogyl, Varizil

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Singulair, Provera, Dostinex, Periactin, Keflex, Cipro, Clomid, Vantin, Cycrin, Kemadrin, Nevirex, Acquire, Iramicina, Valtec, Alprasert,

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Also known as: Metronidazole


Metronidazole vaginal is used to treat women with vaginal infections (eg, bacterial vaginosis).

Metronidazole belongs to the class of medicines known as antibiotics. It works by killing the bacteria or preventing their growth. However, this medicine will not work for vaginal fungus or yeast infections.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain metronidazole. It may not be specific to Acuzole. Please read with care.

Use this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

This medicine is to be used only in the vagina. Use it at bedtime, unless your doctor tells you otherwise.

Do not get it into your eyes, nose, mouth, or skin. If this medicine does get into your eyes, wash them out right away with large amounts of cool tap water. If your eyes still burn or are painful, check with your doctor.

This medicine comes with a patient information leaflet and patient instructions. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Wash your hands with soap and water before and after using this medicine.

Nuvessa™ is available inside a prefilled applicator. The applicator is open at one end where you will insert the plunger and has a pink cap on the other end where the medicine will come out.

Vandazole® is in a tube. You will use an applicator to put the gel into your vagina. The applicator has a plastic tube called a barrel that is open at one end and has a plunger (another piece of plastic that can move inside the barrel) at the other end.

To use the medicine:

To fill the applicator: For cream or gel dosage forms: Nuvessa™: With the pink cap still on, push the tip of the plunger into the open end of the prefilled applicator. Pull the cap off before you insert the applicator into your vagina. Vandazole®: Break the metal seal at the opening of the tube by using the point on the top of the cap. Screw the applicator onto the tube. Squeeze the medicine into the applicator slowly until it is full. Remove the applicator from the tube. Replace the cap on the tube. For vaginal tablet dosage form: Place the vaginal tablet into the applicator. Wet the vaginal tablet with water for a few seconds. To insert vaginal metronidazole using the applicator: For all dosage forms: Relax while lying on your back with your knees bent (or in any position that you feel comfortable). Hold the full applicator in one hand. Insert it slowly into the vagina. Stop before it becomes uncomfortable. Slowly press the plunger until it stops. Withdraw the applicator. The medicine will be left behind in the vagina. Remove the applicator from your vagina. Use each applicator only once, and then throw it away.

To help clear up your infection completely, it is very important that you keep using this medicine for the full time of treatment, even if your symptoms begin to clear up after a few days. If you stop using this medicine too soon, your symptoms may return. Do not miss any doses. Also, continue using this medicine even if your menstrual period starts during the time of treatment.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For bacterial vaginal infections: For vaginal dosage form (cream): Adults—One applicatorful (500 milligrams [mg]), inserted into the vagina. Use the medicine 1 or 2 times a day for 10 or 20 days. Children—Use and dose must be determined by your doctor. For vaginal dosage form (gel): Nuvessa™: Adults and children 12 years of age and older—One applicatorful (5 grams [g]) inserted into the vagina once (at bedtime). Each applicatorful of Nuvessa™ contains 65 mg of metronidazole. Children younger than 12 years of age—Use and dose must be determined by your doctor. Vandazole®: Adults—One applicatorful (5 grams [g]) inserted into the vagina once a day (at bedtime) for 5 days. Each applicatorful of Vandazole® contains 37.5 mg of metronidazole. Children—Use and dose must be determined by your doctor. For vaginal dosage form (tablets): Adults—One 500 milligram (mg) tablet, inserted high into the vagina. Use the medicine once a day in the evening for 10 or 20 days. Children—Use and dose must be determined by your doctor.


If you overdose Generic Acuzole and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Acuzole overdosage: dizziness, seizures, torpor, retching, nausea, lack of balance, problems with coordination, tingling.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Acuzole ER dosage information

Side effects

The most common side effects associated with Acuzole are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Psychotic Reaction with Disulfiram. Use of oral metronidazole is associated with psychotic reactions in alcoholic patients who were using disulfiram concurrently. Do not administer metronidazole to patients who have taken disulfiram within the last two weeks.

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XRD results showed that the anatase TiO2 structure was predominant for TiO2 from DW (TiO2-DW) and TiO2 from SW (TiO2-SW), which were mainly doped with carbon atoms. The enzyme involved was characterized as a NADPH-dependent carbonyl reductase which is strongly inhibited by the plant flavonoid quercitrin but which shows no sensitivity to phenobarbital. This noninvasive technique should be able to replace CT or dimercaptosuccinic acid scintigraphy in many children with urinary tract infections. The as-sprayed coating was chemically treated in 5M NaOH solution at 80 degrees C for 48 h. We have studied the processing of a C-peptide-deleted precursor of neuropeptide Y (NPY) in which the precursor terminates in the sequence Gly-Lys-Arg and does not require any dibasic specific endoproteolytic processing. Heterogeneity, subgroup analysis, sensitivity analysis and publication bias were explored. Integrin receptors and their extracellular matrix ligands have been implicated in the molecular and cellular mechanisms of trophoblast adhesion and migration.

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The existing health service infrastructure in the study area is described and the fragmentation of health services between races, between preventive and curative services and on a geographical basis is highlighted. Embryonic stem (ES) cells were transfected with the insulin-like growth factor (IGF) II gene and were selected with G418. The neuritogenesis of the CAD cells was abolished by inhibiting microtubule polymerization with nocodazole and by blocking microtubule depolymerization with taxol. Current literature data about the role of dietary pattern on the occurrence of colonic diverticulosis, diverticular disease and acute diverticulitis are still too conflicting. Targeting FGF19 binding to its receptor system: a novel therapeutic approach for hepatocellular carcinoma.

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To review the available epidemiological data on the relation between NSAIDs and risk of breast cancer together with interventional studies in established disease. A comprehensive neuropsychological test battery was administered to healthy postmenopausal women who had been treated or not treated with long-term HRT without interruption since menopause. Although the wild-type (wt) AAV requires a helper virus for its optimal replication, we hypothesized that inserting the B19p6 promoter in a recombinant AAV would permit autonomous viral replication, but only in erythroid progenitor cells. Two regions (Northern and Ashanti) covering the northern and southern sectors of Ghana were strategically selected. Two experiments are reported that investigate the effects of saccadic bilateral eye movements on the retrieval of item, associative, and contextual information. Chromatin immunoprecipitation experiments indicate that the MRE11 protein associates with the incoming rAAV genomes and that this association decreases upon cell treatment with DNA damaging agents. Random noise driven pressure and flow time domain data were simulated for three models, which permitted predictions of Zrs characteristics previously reported from 0-4, 4-32, and 4-200 Hz. coli, one that is activated by the sbcB15 mutation and one that is activated by sbcB null mutations.

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The data on patients with pathologically confirmed colorectal cancer who underwent curative surgery at Aga Khan University Hospital, Karachi, Pakistan, between January 1999 and December 2008 were recorded. Here we develop several mouse models in which hypothalamic stem/progenitor cells that co-express Sox2 and Bmi1 are ablated, as we observed that ageing in mice started with a substantial loss of these hypothalamic cells. Mechanical behavior and failure analysis of prosthetic retaining screws after long-term use in vivo. The intra-aortic balloon pump (IABP) is commonly used for decreasing myocardial oxygen demand by systolic unloading in perioperative heart failure. The tissue response to photopolymerized PEG-p(HPMAm-lactate)-based hydrogels. The objective was to assess the clinical outcome of three schemes of HDR-BT boost. We found that genes and proteins of C1QC and C1RL were co-differentially up-expressed in patients with COPD or AECOPD, while haptoglobin (HP), ORM1, SERPING1, and C3 were identified as a panel of AECOPD-specific immunomodulatory mediators. This diagnosis was confirmed by angiography and the patient underwent successful repair. In situ hybridization analyses of mouse embryonic, newborn, and adult tissues were conducted to evaluate the spectrum of gba mRNA expression.

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Bayesian networks were fit for each outcome (current hot flashes, hot flashes before the end of the study, hot flash severity, hot flash frequency, and age at first hot flashes) separately and together with a list of risk factors (estrogen, progesterone, testosterone, body mass index and obesity, race, income level, education level, smoking history, drinking history, and activity level). Lichen planopilaris in a Latin American (Chilean) population: demographics, clinical profile and treatment experience. Generally workers perceived restructuring negatively and did not want it done. Since their introduction in 1985, Medicare health maintenance organizations (HMOs) have had mixed results, and little research has been completed on what factors lead to a successful experience for capitated physicians in Medicare HMOs. Shevach discusses the current understanding of the different subsets of T regulatory cells and provides a perspective on the current areas of uncertainly and controversy in the field. Medical regulation is rapidly changing with claims that systems such as revalidation/relicensing will reassure the public. This brief review summarizes features of the zebrafish, Danio rerio, that make it a suitable model organism for studies of regulatory physiology. This PTPase cDNA panel, spanning probes for receptor-type as well as cytoplasmic-type family members, was used to monitor RNA expression levels in keratinocyte fractions isolated from murine epidermis and in keratinocyte cell cultures.

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Our analysis showed that the proposed data integration method is able to improve the accuracy of prediction of anticancer drug responses in cell lines, and can identify consistent and novel drug-cancer gene associations compared to existing data as well as aid in drug repositioning. We examined the lesions by bronchoscopy, and the biopsy specimen revealed fungus bodies of Cryptococcus with granulomatous inflammation. Signal Construction-Based Dispersion Compensation of Lamb Waves Considering Signal Waveform and Amplitude Spectrum Preservation. The mucous cells are typical in appearance, with lucent granules that contain an assortment of scattered vermiform or particulate densities. We have used a fluorescence microscope and flow cytometer to evaluate apoptotic events in cells treated with ADR. Team-based learning (TBL) has become a more commonly recognized and implemented pedagogical approach in curricula of numerous disciplines. IFN-gamma-pre-treated SCCHN cells were less effective in competing with untreated targets in cold target inhibition assays and in inducing cytokine production from NK cells in co-incubation experiments.

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Differentiation of neurons in the primary nervous system is reduced in n1-src-knockdown embryos, accompanied by a severely impaired touch response in later development. In addition, it involves a complex manufacturing process to produce it. Comparison of the efficacy and adverse effects of nifedipine and indomethacin for the treatment of preterm labor. This article covers the basic knowledge and technical skills required to perform simple biopsies in general practice. This study elicited the views of HIV-uninfected women with personal experience taking PrEP during pregnancy. A range of individual, social and health system and services factors may determine successful transition preparedness among adolescents in Cambodia.

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But in real-life, uncertainty is an important factor as data is collected using various types of sensors that are more or less accurate. Intravenous injection of protamine sulfate or quarternized chitosan derivative to guinea pigs after injection of 1 mg/kg (100 aXa U/kg) low-molecular-weight heparin (clexane) led to shortening of plasma clotting time in the ReaClot Heparin test and to prolongation of plasma amidolytic activity in the factor Xa chromogenic substrate test. Further studies are warranted for clarifying the mechanisms of this cytokine in the prevention of HCV transmission. Neoplastic keratinocytes responded to growth stimulation by epidermal growth factor and cholera toxin as do normal keratinocytes. This cross sectional descriptive study was carried out to determine frequency of hypertensive disorders of pregnancy and its impact on maternal and perinatal outcome. Apart from a history of significant weight loss, there were no other signs or symptoms indicative of hyperthyroidism. Factors related to glucose metabolism parameters were explored by multilinear regression analysis. A hotspot in the glucocorticoid receptor DNA-binding domain susceptible to loss of function mutation. 24 to 48 h after beginning of therapy there were effective concentrations of nystatin in the faeces. Thus, selection for adult stress resistance has resulted in correlated changes in larval physiology.

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The length of stay prior to surgery increases the risk of postoperative infections (PIs) in several surgical settings, such as cardiac, orthopedic, and general surgery. However, studies using a BN antagonist and BN receptor knockout mice suggested that the inhibitory effects of PAMP on feeding and gastric emptying were mediated not via BN receptor but via another receptor specific for PAMP. This transgenic system helps define the range of cellular changes associated with altered expression of PSCA, shows that transcriptional control is a major component regulating PSCA levels, and provides a useful tool to study subpopulations of prostate epithelial cells and factors that regulate the PSCA promoter. Alpha(2,3)-linked sialic acid residues increased from Stage I to Stage II tumors but decreased in advanced carcinomas. The reciprocal influences of thymic lymphocyte and nonlymphocyte populations, i.e. The stabilizing effect of Mst was much greater on N-terminally truncated hSav mutants, as long as they retained the ability to bind Mst. Index profiles can be calculated only from simple algebra using the Fourier coefficients of the fringe shift and a matrix independent of fiber parameters.

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New users of both single and fixed combined ICS have alarming low persistence rates with ICS-treatment in the first year of follow-up. Acamprosate efficacy in alcohol-dependent patients: summary of results from three pivotal trials. Religiousness and spirituality are important to most Americans, and evidence suggests that they may contribute to both addiction and recovery. The potential application of such tailorable materials and structures as they relate to the enhancement of sensitivity in chalcogenide glass based planar chemical sensor device design is presented. Heart rate perturbation in chick embryos: a comparison of two methods. We hypothesized that obesity and diabetes were involved in the pathophysiology of AF by means of promoting a lipotoxic phenotype in atrial muscle, and that AF predicts mortality in cardiac care patients. As there is no standardized normal value in China at present, this study will provide a normal value of lung function determination by impulse oscillometry for children in Chengdu area. Knowledge of and satisfaction with the approval of the nurse prescription of nurses studying a masters degree and specialty in the University of Barcelona.

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With a broader understanding of the frequency and effects of neurological injury from cardiac surgery and its implications for patients in both the short term and the long term, we should be able to give personalised treatments and thus preserve both their quantity and quality of life. Spectrophotometers are a good substitute for visual color selection methods. The Japanese writing system is unique in that it is composed of two different orthographies: kanji (morphograms) and kana (syllabograms). Initial experiences with the enhanced recovery after surgery (ERAS) protocol in open radical cystectomy. Neonatal rats submitted to experimental ureteral obstruction were treated with either vehicle or rosuvastatin for 14 days. The detection of haemagglutination-inhibiting antibodies against genus Flavivirus indicated that there was recent contact between the analysed domestic pigeons and these arboviruses. The options, recommendations, and research suggestions in this report should outline for nutrition scientists the database needed before any new dietary cleocin t gel price recommendations or changes in nutrition policy concerning trans fatty acids can be made. There was some evidence of better neurocognitive performance in those with partial symptom remission at follow-up.

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Ophthalmic examination, visual field (VF) examination, and brain magnetic resonance imaging (MRI) were performed. Quantitative assessment of corneal viscoelasticity using optical coherence elastography and a modified Rayleigh-Lamb equation. Angiotensin-converting enzyme (ACE), which metabolizes many peptides and plays a key role in blood pressure regulation and vascular remodeling, is expressed as a type-1 membrane glycoprotein on the surface of different cells, including endothelial cells of the heart. Different Responses in MMP/TIMP Expression of U937 and HepG2 Cells to Dengue Virus Infection. Four decades of clinical and basic research have laid a solid base when should nexium tablets be taken for clinicians to choose the best possible treatment for patients with melanoma. A 74-year-old man presented with a 4-month history of swelling in the right upper lid. Population pharmacokinetics and pharmacodynamics of oral etoposide. In addition, expression of wild-type (WT) p53 in a variety of human tumor cell lines, as well as murine fibroblasts, results in down-regulation of NOS2 expression through inhibition of the NOS2 promoter. The drug-binding activity of the multidrug-responding transcriptional regulator BmrR resides in its C-terminal domain.

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Assessment of values, utilities and preferences in cancer patients. To compare the rates of energy expenditure at given rating of perceived exertion (RPE) levels xanax drug card quizlet among 6 different indoor exercise machines. IS TRAUMA RESUSCITATION SAME AS CLASSICAL CARDIAC RESUSCITATION?. Previous research suggests that the Great Depression led to improvements in public health. This review will discuss the role of icotinib in NSCLC, and its potential application and ongoing investigations. Treatment of streptococcal pharyngitis with once-daily compared with twice-daily amoxicillin: a noninferiority trial. As shown by SDS-electrophoresis the two nucleoproteins shared a set of proteins (apparent Mr 11,000 to 15,000), and differed in the DNA moiety (approximately 150 bp in NP1, approximately 350 bp in NP2). Differential diagnostic difficulties in a case of probably spontaneous cryptococcus meningitis in a young girl are the reason for an extensive presentation of this case. We successfully isolated exosomes from human breast milk and plasma. These include the potential line of histogenesis and whether the tumor is benign or malignant, and low or high grade.

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In this paper, we focus our interest on the dynamics alterations of the tumor-stroma interface at the ultrastructural level and to detect BRCA1 and BRCA2 mutations using next generation sequencing (NGS) of breast tumor tissue. All the patients were conservatively managed using intravenous fluids, antibiotics, anti-tussive and anti-fibrinolytic drugs. Reverse-phase HPLC analysis was performed on a C18 column by the use of a shallow acetonitrile gradient in trifluoroacetic acid/water. This report describes a 21-year-old man who presented with chest pain and dysphagia 1 day after using ecstasy. Effect of capitonnage and cystotomy on outcome of childhood pulmonary hydatid cysts.

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Protein synthesis and antioxidant capacity in aging mice: effects of long-term voluntary exercise. It is suggested that this may be due partly to the reduction in testicular perfusion. In sub levaquin max daily dose -Saharan Africa, HBV vertical transmission continues to be reported and it remains an important public health problem. Obviously DNA microarrays technology may be useful in identifying intestinal pathogens and have a wide prospect. Association of increased tumor cell responsiveness to prostaglandin E2 with more aggressive tumor behavior. Serum albumin and osmolality inhibit Bdellovibrio bacteriovorus predation in human serum.

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Red blood cell alloimmunization in sickle cell disease: listen to your ancestors. Rare conditions are sometimes ignored in biomedical research because of difficulties in obtaining specimens and limited interest from fund raisers. We performed a retrospective analysis of 99 eyes (53 subjects) with nonproliferative MacTel who underwent fundus fluorescein angiography and spectral domain optical coherence tomography using Cirrus HD-OCT. The results provide insights into the influence of changes in the dynamics of water on the proton-transfer processes. Importance of specific adenosine N3-nitrogens for efficient cleavage by a hammerhead ribozyme. Questions asked of couples focused on (a) the process of being diagnosed and treated for prostate cancer, (b) what the experience was like for them as a couple, (c) what was helpful, harmful, and surprising throughout the experience, (d) what they currently needed most as a couple, and (e) what advice they had for other couples.

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We present a case with a pedunculated tumor in the nasopharyngeal vault and the preoperative biopsy revealed a thyroid-like papillary adenocarcinoma. Reduction in reproductive lifespan of tissue inhibitor of metalloproteinase 1 (TIMP-1)-deficient female mice. The methodology can be divided into two parts: the characterization method of macro-contact and the analysis of the slope stability. A coordinated plan incorporating continuing staff education, organ donation policy refinement, and increased visibility and availability of organ procurement agency personnel can substantially increase organ donation at an urban trauma center. By targeting the topic of fungal virulence mechanisms from various angles and in the context of plant and human hosts, some common grounds and exciting perspectives could be deduced during this vibrant scientific event. In this regard, we report that phosphorylation of Shp2 at tyrosine 542 and its translocation to the postsynaptic compartment are integral processes in synaptic scaling. Patient randomization was stratified according to disease/treatment status and olmesartan medoxomil generic vs benicar regional nodal disease status. Surgically, all the patients underwent posterior reduction and synthesis.

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Chaotic phase synchronization in small-world networks of bursting neurons. llex paraguariensis decreases oxidative stress in bone and mitigates the damage in rats during perimenopause. Optimization of optical parameters and electric field distribution in multilayers. Our purpose was to demonstrate which value of packing density is required to produce a durable occlusion. Photoabsorption spectra of Ti8C12 metallocarbohedrynes: Theoretical spectroscopy within time-dependent density functional theory. We experienced a significant number of elevated total thyroxine values in patients with normal thyroid stimulating hormone and thyroxine binding globulin concentrations using the Beckman Access and hypothesized that these were due to a sample matrix effect.

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We compared five different types of conductive (DTL type) yarn (differing in terms of mass, number of filaments, and crimping degree) in order to determine whether we could identify one that would be better suited for the recording of ERGs. They transiently appear within a definite developmental time-period between embryonic day 19 and postnatal day 17 and are only associated with neuronal cells. How a new stratified adaptive phase II design could improve targeting population. The ratio between these was constant, suggesting a strictly parallel secretion. To date, basic science research into the pathogenesis of prolapse has been limited.

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