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Actical (Calcitriol)
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Actical

Actical is an active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia. Actical is a biologically active calcitrophic hormone with anti-osteoporotic, immunomodulatory, anticarcinogenic, antipsoriatic, antioxidant, and mood-modulatory activities.

Other names for this medication:
Actical, Alcee, Alfabond, Alfacal, Alfarich, Aristrol, Calbec, Calbory, Calcibest, Calcicare, Calcikind, Calcirol, Calfa, Calsonic, Calsure, Calzem, Citroj, Coecoral, Denscal, Koncal, Lctrol, Novadee, Ostriol, Primacal, Rical, Riecal, Roical, Sorvate, Sunmic, Tobalt, Vitalpha

Similar Products:
Dostinex, Loxitane, Dilantin, Cialis, Sporanox, Ceftin, Altace, Ultram, Abilify, Isryl, Levonidin, Regestrone, Rosumed, Clindexcin, Polfamycin, Ebivol, Furomet, Norten,

Also known as: Calcitriol

Description

Generic Actical is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Actical are intestine and bone. Generic Actical receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Actical may also act on the kidney and the parathyroid glands. Generic Actical is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Actical has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Actical, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Actical in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Actical produces other independent beneficial effects. Actical is also known as Calcitriol. Generic Actical treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Actical is Calcitriol. Brand name of Generic Actical is Actical.

Dosage

Generic Actical is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Actical suddenly.

Overdose

If you overdose Generic Actical and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Side effects

The most common side effects associated with Actical are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

If you are taking a dietary supplement without a prescription, carefully read and follow any precautions on the label. For these supplements, the following should be considered:

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The effects of perceived quality on behavioral economic demand for marijuana: A web-based experiment. The discoveries of novel functional adaptations of the hypothalamus and anterior pituitary gland for physiological regulation have transformed our understanding of their interaction. This study employed EEG source localisation procedures to study the contribution of motor preparatory and attentional processing to foreperiod activity in an S1-S2 motor priming task. We show that the SWI4 and SWI6 genes are required for formation of the CCBF-promoter complex in vitro, either as components of CCBF or as modulators of CCBF activity. Incomplete ischemia was produced by permanently occluding one carotid artery, while temporarily occluding the other. Taurine protects methamphetamine-induced developmental angiogenesis defect through antioxidant mechanism.

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High-impact articles that enhanced understanding of ACL injury aetiology, rehabilitation, prevention and adaptations after reconstruction were selected. We reviewed the current evidence for an impact of osteoporosis treatments on bone repair. The pharmacokinetic behavior of KRN7000 in the clinical trial could be described by a three-compartment model. To observe protective effects of polydatin (PD) during lung ischemia/reperfusion injury (LI/RI) and investigate its potential mechanism . Prevalence of Toxoplasma gondii and Neospora caninum antibodies in Spanish ibex (Capra pyrenaica hispanica). Delirious mania also known as Bell mania is a syndrome of excitement, delirium, and psychosis, of acute onset. Additionally, human macrophage primary culture expressed APRIL on the cell surface.

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Efficacy and safety of melphalan, arsenic trioxide and ascorbic acid combination therapy in patients with relapsed or refractory multiple myeloma: a prospective, multicentre, phase II, single-arm study. Surprisingly, transcriptome analysis revealed an insufficient innate immune response of macrophages only to HPAIV infections. Given the increasing worldwide prevalence of obesity, NAFLD has become the most common cause of chronic liver disease and therefore is a major global health problem. We studied the in vitro hydrolysis of lipoprotein phospholipids by group IIa and group V sPLA(2), two structurally related enzymes with differing phospholipid specificities. Febrile temperatures can synchronize the growth of Plasmodium falciparum in vitro. Resolution is best in propanol, which precipitates and immobilizes the DNA and provides a fluid imaging environment where adhesive forces are minimized. Because the main concerns of this study were awareness and preparedness, which required human interaction, the SP methodology was the optimal simulation modality. The purpose was to determine whether myostatin levels are higher in paretic vs nonparetic muscle and the effects of resistive training (RT) on paretic and nonparetic mid-thigh muscle composition and myostatin mRNA expression in stroke survivors. Membrane distal cytokine binding domain of LIFR interacts with soluble CNTFR in vitro. High susceptibility to paraquat-driven lipid peroxidation of cultured hepatocytes loaded with linolenic acid.

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LF enhanced NK in a dose-dependent manner, but similar concentrations paradoxically inhibited ADCC. The organized transport of essential biological materials throughout the neuron is required to support its growth, function, and viability. The upper lip is formed by the fusion of facial processes, a process in which many genetic and environmental factors are involved. Pharmacological treatment should be implemented when glucose values reach up above 12mmol/l (216mg/dl) twice a day. Data were collected from 161 racially/ethnically diverse, inner-city high school students, 14 to 19 years of age.

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In chickens, a novel GH-responsive gene (GHRG-1) has been identified as an intracellular marker of GH action, since this gene is not expressed in GH-resistant dwarfs with dysfunctional GHRs and in normal chickens it is upregulated by exogenous GH. Effect of meralluride on distal nephron transport of sodium, potassium and chloride. The concentration of ccfDNA in plasma was measured by quantitative real-time polymerase chain reaction at baseline to 24 weeks in every 4-week period from 30 patients and 21 healthy individuals. Moreover, employment of a transcriptome-phenotype matching approach revealed groups of genes associated with robustness towards heat and/or oxidative stress. A morphological, immunophenotypical, and ultrastructural study of two typical cases.

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Videothoracoscopic resection of benign neurogenic tumors of the posterior mediastinum. The fate of lactaldehyde depends on the respiratory growth conditions. atrophaeus were inactivated in the flare, indicating that spores that become re-entrained in landfill gas may not escape the landfill as viable, apparently becoming completely inactivated as they exit through a landfill flare. Mathematical models can help to predict the population-level effects and the cost-effectiveness of a variety of ACF strategies on different risk populations. Could the Chagas disease elimination programme in Venezuela be compromised by reinvasion of houses by sylvatic Rhodnius prolixus bug populations?. Under general anesthesia the patient is positioned laterally, and a substantial and meticulous debridement of the defect is performed, as is the identification and preparation of the target vessel, which is preferentially the posterior tibial artery at the calf, or more proximally the popliteal or femoral artery from the medial side as well as concomitant veins/the great saphenous vein. Although the risk of nerve injury may be higher, a thorough knowledge of frontotemporal anatomy and careful dissection will minimize this risk. Interviews were audio recorded and transcribed verbatim for analysis using NVIVO11.0 software. Response of small pulmonary arteries to unilobar hypoxia and hypercapnia. This study assessed the proportion of adults with previously diagnosed diabetes mellitus (DM) who met selected preventive practices and treatment goals according to the American Diabetes Association (ADA) standards of medical care.

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Loss of blast cell procoagulant activity and improvement of hemostatic variables in patients with acute promyelocytic leukemia administered all-trans-retinoic acid. However, three months thereafter, she again required RBC transfusions after developing severe ulcerative colitis. The atrial light chains ALC1 and ALC2 migrated with molecular weights lying between those of the ventricular light chains VLC1 and VLC2. Mixed-effects models were used to estimate EC levels for five maximum zyprexa dosing surface and five underground occupation groups (as a fixed effect) and specific jobs within each group (as a random effect). A review of 14 reported cases and our case of uterine osteosarcoma revealed that this tumor has a biologically aggressive nature, although its histopathological and immunohistochemical features are similar to those of osteosarcomas in soft tissue and bone. Beer intakes were similar to those of some people in the United States. On the basis of isolated sequences rich in histidine residues, two secondary libraries were constructed respectively.

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Prognostic value of cortical evoked potentials in spinal-spinal cord pathology: study of 1 clinical case. These glycoproteins are oligomeric type II integral membrane proteins, which possess haemagglutination and sialidase activity. This is consistent with exonuclease III being required for part of the repair synthesis seen, while DNA polymerase I is strictly required for all repair synthesis. One hundred thirty-eight college students completed self-report measures of affect and coping at two assessment periods 5 weeks apart. Children who die with underlying CCCs increasingly do so at home. The case of a 66-year-old woman with rapidly progressive respiratory distress caused by a massive anterior neck mass with tracheal compression is presented. v-myb and v-myc proteins thus share the same subnuclear location and apparently interact directly with the cellular DNA. The structural proteins of Sindbis virus are translated as a polyprotein precursor that is cleaved upon translation. Rats received one or five injections and were tested after either 30 minutes or 24 hours. Here, we report an initial study of two geothermal sites where mixtures of representative organic solutes (amino acids, nucleobases, a fatty acid and glycerol) and phosphate were mixed with high-temperature water in clay-lined pools.

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basalis adults were more susceptible to the three essential oils than the adults of their hosts C. At the high end of the thermal range, related perciform species from the Mediterranean had a negligible drop in intracellular P(O(2)) across their small-diameter fibres, to a minimum of 5.4 kPa, comparable with that predicted for Trematomus newnesi from the Antarctic (5.6 kPa) with a similar MFD. Results of the treatment of uterine cervix cancer in the Maria Sklodowska-Curie Oncological Institute in 1959. Immunolocalization of proteoglycan types in aortas of pigeons with spontaneous or diet-induced atherosclerosis. Pelvic abscesses are usually the end stage in the progression of an infection.

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To evaluate the effects of clinical guidelines and a targeted DTC advertising campaign on overall and appropriate use of human papillomavirus (HPV) DNA tests. This discrepancy was resolved when the 86-kDa protein was identified as the major coat protein in viruslike particles (VLPs) which is encoded by a double-stranded RNA (L-A RNA). In Part 2 of this review, clinical situations where sirtuins might play a significant role, including longevity, obesity, fatty liver disease, cardiovascular health, neurological disease, and cancer, are discussed. Surgical treatment using The Unit Rod in children with neuromuscular scoliosis. Furthermore, the PK of escitalopram in hippocampus following intravenous injection was not influenced by the valium 10 mg blue pill presence of vascular catheters. The camera system in which a device is used, however, dictates the overall performance which can be achieved. Disruption of the VEGFR-2 leads to a significantly diminished growth cone size.

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However, it is currently difficult to determine which individual initiates vocalizations, or who responds to whom. Resting metabolic rate and protein turnover in apparently healthy elderly Gambian men. There is increasing evidence that these antibodies have a clinical impact in MS treated patients, which is evident some months following the initiation of treatment with IFN?. Characteristics of gait ataxia in spinocerebellar degeneration assessed by means of simple quantitative buy depo provera injection online uk method. Hospitals were selected using the qualitative sampling strategy of maximum variation based on their use of the methods (as reported in a previous mail survey). H-NS control is the result of H-NS binding to extended regions within the pecT, expI, expR and pel genes. Clinical improvement and patient satisfaction were assessed at 2 and 6 months after each treatment. To investigate the relationship between the amount of amiodarone and the major metabolite N-desethylamiodarone found in the lung with the development of toxicity, Fischer 344 and Wistar rats were given 175 mg/kg/day of drug by gavage.

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Overall quality of studies was found to be disappointing with poor reporting often the main problem. In addition, to provide a theoretical basis for the method, we present a graphical interpretation of both the original frequency matrix and the SVD-derived matrix. Hydroxocobalamin was associated with an increase in blood pressure in some volunteers. ATP is an important signalling xenical dose molecule in the peripheral and central nervous system. In all studies the data from animals in either the second or third trimester of pregnancy were compared with the results obtained from non-pregnant females. A number of novel Notch target genes, including the transcription factor TCFL5 and the HOXA cluster, were identified and functionally tested. The therapeutics efficacy of BM-ca awaits its use in clinical trials.

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Perspectives on AIDS in Africa: strategies for prevention and control. The importance of animal health crises has considerably albenza generic increased over the last few years. The basics of obstetric, gynecologic, and neonatal nursing research are discussed in a three-part article series. We show that the COOH modification significantly promoted initial cell adhesion and proliferation over 14days compared to NH2 surfaces. With increasing consumption of betel nut preparation, there was a reduction in RRIV, particularly during deep breathing.

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In darkness, glucose consumption in the photoreceptors was higher than that recorded under conditions of constant illumination with white light. MnTMPyP, a superoxide dismutase/catalase mimetic, decreases inflammatory indices in ischemic acute kidney injury. Adapting concepts from systems biology to develop systems exposure event networks for exposure science research. A bile salt (sodium taurodeoxycholate, NaTDC) was used to prevent phase separation between silica and lipid in self-assembled long-chain diacyl phosphatidylcholine/SiO(2) films. The effect of CD4 receptor downregulation and its downstream signaling molecules on HIV-1 latency. Predicting viruses accurately by a multiplex microfluidic loop-mediated isothermal amplification chip. Subsequent treatment of pulmonary failure was successfully managed with ECMO. Eighty patients of both sexes, aged between 18 and 63 years, who had hypertrophic scars and keloids, were admitted to the trial.

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In the patient with the acquired lysosomal storage disease, massive tissue infiltration with activated foamy macrophages was observed. To assess frequency and determine the factors associated with Chlamydia trachomatis, herpes simplex virus type 2, and hepatitis B seropositivity among Pakistani pregnant women and their husbands in Norway. The antigen defined by MCA-97 was estimated to be a nonsialylated high-molecular-weight glycoprotein containing galactose and N-acetylglucosamine in its determinant. Homologous nucleic acid sequences can correct mutations by inducing recombination or mismatch repair. Adapting the selective periodic health exam to a college-aged population. Two reviewers independently searched for abstracted information. An important corollary to the recent advances in our understanding of the primary cause of Duchenne muscular dystrophy, is the validation of genuine genetic homologues as animal models of the disease in which potential therapies can be tested. A four-generation European kindred presenting with FAME, including 18 members, is described.

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CagA, the first identified effector protein of the cag-PAI, is translocated into eukaryotic cells and tyrosine phosphorylated (CagAP-tyr) by a host cell tyrosine kinase. The authors report the case of a patient who developed irreversible cardiovascular collapse during a laparoscopic cholecystectomy. An original technique that allows reinforcement against various causes of dehiscence is described. Human immunodeficiency virus type 1 (HIV-1) infection of the central nervous system: an evaluation of cytokines in cerebrospinal fluid. It is usually more successful to encourage the adoption of new behaviors and attitudes or redirect them in a similar direction than to ask people to give up a valued behavior. Therefore, the hepatic metabolism of P would not be affected by the slower absorption at a single oral dose of 60 mg. However, some of the remaining organ of Corti cells express Myo7a at late postnatal stages and are innervated by remaining afferent fibers. Carcinogenicity of ethylene oxide and 1,2-propylene oxide upon intragastric administration to rats. Standard output includes a spreadsheet-ready text file and an array of publication-quality figures. A clinical and molecular project on gonadoblastoma needs international collaboration.

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In lissencephaly, there was no relationship between severity, deletion size, or appearance of the pontocerebellar tract. Pharmacological modulation of the glucagon-like peptide-1 (GLP-1) system has emerged as a new therapeutic option for treatment of diabetes mellitus. In Seattle, elevated school drinking water lead concentrations are not a significant source of lead exposure in school-age children. Interference of thiosulfate with potentiometric analysis of cyanide in blood and its elimination. Should post-traumatic thoracolumbar Frankel A paraplegia be operated as an emergency?. There are also new findings on the physiological predictors of individual differences in emotional behavior and experience, and on the role of autonomic arousal in emotional memory. To obtain a congruent joint surface after refixation, the oblique osteotomy should be directed perpendicularly to the articular surface of the tibia at the intersection between the tibial plafond and medial malleolus. Relationship between choline derivatives and mouse erythrocyte membrane antigens revealed by mouse monoclonal antibodies. Cemented or cementless fixation was used based on a randomization protocol. He was initially treated with whole brain irradiation but subsequently developed recurrent disease in the spinal cord manifested by paraplegia.

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