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Acema (Tramadol)

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Acema is used for the management of pain in adults. Although it's a little weaker than other opioids, it can still be addictive and habit-forming. Acema is available as both an immediate-acting tablet and an extended-release tablet.

Other names for this medication:
Armadol, Arodol, Avdol, Cormadol, Eltram, Esgiypyrin, Gemodol, Jpdol, Madol, Midol, Nobligan, Nopidol, Painadol, Paintrol, Ramcet, Redimol, Relidol, Rimol, Ryzolt, Sigmadol, Simol, Spasteez, Standol, Traceta, Tramacip, Tramadex, Tramest, Tramospas, Trampar, Trazac, Tremtec, Trofel, Tryme, Ultracon, Ultrax, Xtram

Similar Products:
Differin, Sustiva, Nolvadex, Rocaltrol, Prograf, Plavix, Geodon, Cozaar, Suprax, Mysoline, Glysar, Calasto, Donmet, Elcold, Fosicombi, Estimet, Mucorespules,

Also known as: Tramadol


Acema (tramadol) is a pain medicine similar to an opioid. It acts in the central nervous system (CNS) to relieve pain.

Acema is used to treat moderate to severe pain in adults.

The extended-release form of tramadol (Acema ER) is for around-the-clock treatment of pain. Acema ER is not for use on an as-needed basis for pain.


Follow the directions on your prescription label and read all medication guides. Never use Acema ER in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to take more of Acema ER.

Never share Acema ER with another person, especially someone with a history of drug addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medicine where others cannot get to it. Selling or giving away this medicine is against the law.

Stop taking all other opioid medications when you start taking Acema ER.

Acema ER can be taken with or without food, but take it the same way each time.

Swallow the capsule or tablet whole to avoid exposure to a potentially fatal overdose. Do not crush, chew, break, open, or dissolve.

Measure liquid medicine with the supplied syringe or a dose-measuring device (not a kitchen spoon).

Never crush or break a Acema ER pill to inhale the powder or mix it into a liquid to inject the drug into your vein. This practice has resulted in death.

You may have withdrawal symptoms if you stop using Acema ER suddenly. Ask your doctor before stopping the medicine.

Store at room temperature away from moisture and heat. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.

Do not keep leftover Acema ER. Just one dose can cause death in someone using it accidentally or improperly. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, mix the leftover medicine with cat litter or coffee grounds in a sealed plastic bag throw the bag in the trash.

Detailed Acema ER dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Acema are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Acema ER if you are allergic to it, or if you have:

severe asthma or breathing problems; a stomach or bowel obstruction (including paralytic ileus); if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or if you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine).

Acema ER should not be given to a child younger than 12 years old. Acema ER should not be given to anyone younger than 18 years old.

Do not give Acema ER to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.

Seizures have occurred in some people taking Acema ER. Your seizure risk may be higher if you have ever had:

a head injury, epilepsy or other seizure disorder; drug or alcohol addiction; or a metabolic disorder.

Tell your doctor if you have ever had:

breathing problems, sleep apnea; liver or kidney disease; urination problems; problems with your gallbladder, pancreas, or thyroid; a stomach disorder; or mental illness, or suicide attempt.

If you use Acema ER during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Ask a doctor before using Acema ER if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.

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Incentives to sparingly order diagnostic tests, make referrals to specialists, or discharge patients early, expand exposure to medical professional liability. Basing on extensive experimental and clinical examinations the possibility to distinguish between the luxated and the non-luxated hip as well as the diagnosis of certain kinds of dysplasia are demonstrated with the aid of examples. The incidence of sleep deprivation in the United States is generally unacknowledge by the public as well as health care professional. This is probably due to excess influx of calcium ions, leading to activation of proteases. The ultrasound measurements aided in refining our operative technique. Five fresh-frozen cadaveric hip-to-toe lower extremity specimens were used for this study (10 knees). Use of tanned-cell hemagglutination to demonstrate circulating antibody against an oral spirochete. Helicobacter pylori is a globally spread bacterium causing gastritis in man. The current overuse and misuse of meta-analyses on sublingual immunotherapy: the case of grass pollen allergy.

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Assembling nanoparticle catalysts with nanospheres for periodic carbon nanotube structure growth. The root-rot and damping-off causative agent Pythium aphanidermatum and the CAA fungicide mandipropamid (MPD) were used to investigate the molecular basis of CAA tolerance. The study used data from the Nairobi Urban Health and Demographic Surveillance System in two slums in Nairobi city, where a total of about 60,000 individuals living in approximately 23,000 households are under surveillance. Paleomicrobiology to investigate copper resistance in bacteria: isolation and description of Cupriavidus necator B9 in the soil of a medieval foundry. Based on the available evidence in this preliminary short-term retrospective review, positive microbiology from donated femoral heads has no clinical implication in the donors. Longitudinal volume changes of target structure were evaluated, and usefulness of transvaginal 3D ultrasound was evaluated. However, immunoelectron microscopy showed the same relative amount of bound EGF localizing to caveolae on incubation with high and low concentrations of EGF, not supporting rapid recruitment of EGFR to caveolae. At the same time the neuroleptic increases motor asymmetry, which appears in response to apomorphine, and changes the nature of interhemispheric relationships. Efficiently shifting between tasks is a central function of cognitive control. Solving the health and hygienic problems in the Strandzha-Sakar district.

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Intraabdominal metastatic carcinoma: unusual presentation and potential pitfall in CT evaluation. MR anatomy of the proximal cisternal segment of the trochlear nerve: neurovascular relationships and landmarks. The most striking effect observed in nerve homogenates of ACR-treated rats was a marked decrease in phosphorylation of an 80-kDa protein. The ratio of total villous surface area to infant weight, length and head circumference was reduced in the light for dates infants. The arrow poison was prepared from the bark of a tree, known locally as Tike-Uba. The most severe form is caused by biallelic mutations of KCNJ11 and ABCC8 genes that encode both potassium channel subunits, whereas their heterozygous mutations as well as enzymatic defects (GLUD1, HADH, GCK) lead to milder presentation. The ligand binding was detected by complement mediated lysis and agglutination with specific anti-IgA serum.

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Freezing single molecule dynamics on interfaces and in polymers. Between 1972 and 1993 equilibrium and audiological examinations were made on 73 patients who had been diagnosed to suffer from vestibular neuronitis. Subjects were randomly assigned to one of two groups: Waterpik Water Flosser (WF) plus manual tooth brushing or Sonicare Air Floss (AF) plus manual tooth brushing. The combination of ZnO nanorods with DNR induced the remarkable improvement in the anti-tumor activity, which has been demonstrated by the flow cytometry, MTT assay and nuclear DAPI staining. An algebraic analysis of the two state Markov model on tripod trees. Rats were injected with STZ or vehicle and handled daily to minimize stress. Hypotension, dizziness, salivation, and sedation are the most frequently reported adverse effects and tend to subside over time. The influence of a deficiency of vitamin B(1) and of riboflavin on the reproduction of the rat. The protein was shown to be incorporated into a protein-lipid complex of uniform density by density gradient sedimentation equilibrium.

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A questionnaire-based study regarding local induction practices among all Danish delivery units and a cross-sectional population-based registry study based on data from the Danish Medical Birth Registry (DMBR) in the years 2009-2012. Coordinated events: FGF signaling and other related pathways in palatogenesis. Self-reported BMI in the NHANES differs markedly from self-reports in the NHIS and BRFSS. In particular, female patients needed social support, as they received less support from their families than men did. For patients with poor bone quality or abnormal morphology, the mid-head resection technique is an alternative, bone-conserving procedure but whether this technique results in acceptable complications and survival is unknown. Thread carpal tunnel release is potentially a safe, quick, and effective procedure to transect the transverse carpal ligament. To assess the effect of a PPI, rabeprazole, on gastric volume and emptying and postprandial symptoms. The use of high-dose corticosteroids as adjunctive therapy in septic states has been extensively debated in the literature, but no clear consensus has been reached. A defective type 1 immune response to RVs may be implicated in the pathogenesis of virus induced exacerbations of asthma.

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Using the baseline data from a cluster-randomized behavioral intervention trial, we examined the cross-sectional associations of frequency of information and communication technologies (ICT) use among female public housing residents, as well as the variation of ICT use across demographic and health-related variables. Attempts to obtain informed consent were made in compliance with the resolution 196/96 of the Brazilian National Health Council and determination of INCA Research Ethics Committee. More recently there have been developments in the use of monoclonal antibodies to measure oncogene products or proliferation markers in addition to DNA content. Time course of changes in plasma vasopressin during atrial distension. A more extensive population of HC alpha-expressing cells appeared several days before birth in a pattern which could represent the prenatal initiation of HC alpha expression in working myocardial cells. The distribution of flagyl 500 ovule pour quel infection T-1982, a new semisynthetic cephamycin antibiotic, was studied with whole body autoradiography in normal male mice, pregnant mice and experimental pyelonephritic mice following a single intravenous administration of 80 mg/kg of 14C-T-1982. This is evidenced by the de novo synthesis of transcripts of interleukin-1 alpha and interleukin-12 p40/p35 as well as transcripts of MHC class II. We isolated circulating proteasomes from the plasma of 2 patients with rheumatoid arthritis and 2 with systemic lupus erythematosus and from human plasma from healthy donors. Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences.

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