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Accupain (Tramadol)

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Accupain is used to help relieve moderate to moderately severe pain. Accupain is similar to opioid analgesics. It works in the brain to change how your body feels and responds to pain. Pain medications work best if they are used as the first signs of pain occur. If you wait until the pain has worsened, the medication may not work as well.

Other names for this medication:
Acuvin, Atdol, Dolfre, Dolmeri, Domadol, Formador, Inodol, Kamadol, Lagesic, Leedol, Medol, Movon, Nictram, Nomadol, Nosdol, Ondol, Opigesic, Orchidol, Oshdol, Pacadon, Paxmax, Postadol, Ramadol, Ramax, Rimol, Soztram, Standol, Topspas, Tramache, Tramadol, Tramaflam, Tramagesic, Tramared, Tramospas, Transic, Tranzat, Trapain, Trofel, Trydol, Ultraspas, Ultrazac, Veeradol, Zamadol

Similar Products:
Zithromax, Ilosone, Dostinex, Tofranil, Cycrin, Micardis, Hyteron, Atarax, Smicet, Enipaxol, Mustopic, Carbamac, Moduretic, Quetic, Kaprolam, Alzolam,

Also known as: Tramadol


Accupain (tramadol) is a pain medicine similar to an opioid. It acts in the central nervous system (CNS) to relieve pain.

Accupain is used to treat moderate to severe pain in adults.

The extended-release form of tramadol (Accupain ER) is for around-the-clock treatment of pain. Accupain ER is not for use on an as-needed basis for pain.


Follow the directions on your prescription label and read all medication guides. Never use Accupain ER in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to take more of Accupain ER.

Never share Accupain ER with another person, especially someone with a history of drug addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medicine where others cannot get to it. Selling or giving away this medicine is against the law.

Stop taking all other opioid medications when you start taking Accupain ER.

Accupain ER can be taken with or without food, but take it the same way each time.

Swallow the capsule or tablet whole to avoid exposure to a potentially fatal overdose. Do not crush, chew, break, open, or dissolve.

Measure liquid medicine with the supplied syringe or a dose-measuring device (not a kitchen spoon).

Never crush or break a Accupain ER pill to inhale the powder or mix it into a liquid to inject the drug into your vein. This practice has resulted in death.

You may have withdrawal symptoms if you stop using Accupain ER suddenly. Ask your doctor before stopping the medicine.

Store at room temperature away from moisture and heat. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.

Do not keep leftover Accupain ER. Just one dose can cause death in someone using it accidentally or improperly. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, mix the leftover medicine with cat litter or coffee grounds in a sealed plastic bag throw the bag in the trash.

Detailed Accupain ER dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Accupain are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Accupain if you are allergic to tramadol, or if you have:

severe asthma or breathing problems; a stomach or bowel obstruction (including paralytic ileus); if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or if you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine).

Accupain should not be given to a child younger than 12 years old. Accupain ER should not be given to anyone younger than 18 years old.

Do not give Accupain to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.

Seizures have occurred in some people taking Accupain. Your seizure risk may be higher if you have ever had:

a head injury, epilepsy or other seizure disorder; drug or alcohol addiction; or a metabolic disorder.

To make sure Accupain is safe for you, tell your doctor if you have ever had:

breathing problems, sleep apnea; liver or kidney disease; urination problems; problems with your gallbladder, pancreas, or thyroid; a stomach disorder; or mental illness, or suicide attempt.

If you use tramadol during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Ask a doctor before using tramadol if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.

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Sugars are the primary products of CO2 fixation, a metabolic pathway that is rate limited by this solar energy conversion. Analysis revealed that this gene cluster was nestled amid numerous repetitive elements. In 125 cases accurate positioning of the catheter was seen on CXR. Because the focus of attention increasingly turns to optimizing outcomes and utilization of healthcare resources, it is worthwhile to review the array of available tools and techniques for quantifying postoperative outcomes after knee arthroplasty and identify how these might be used to guide refinement of the treatment to achieve even better and more predictable outcomes. Stress affected postnatal depression directly and maternal role competence and satisfaction indirectly, via learned resourcefulness and social support. In the hypercholesterolaemic group there was no flow-dependent arterial relaxation, indicated by the area under the curve of percentage diameter variation as a function of time.

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The synthesis of a new rigid spacer based on carbohydrate-triazole repeating units and their incorporation into divalent systems is described. This is a brief review of 42 cytokines and interleukins that are involved inflammatory and immune responses. Ameliorative effect of p-coumaric acid, a common dietary phenol, on adjuvant-induced arthritis in rats. We need to ensure that the assessment approaches specified in the draft REACH legislation and Technical Guidance are able to evaluate what drug works like zantac EDCs efficiently. Concentrations of endosulfan sulfate and methoxychlor were found to be highest in the summer and winter periods, respectively.

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Views of nature have been reported to relieve stress and pain, making nature an ideal medium for use in healthcare settings. Tryptophan, tyrosine, asparagine, and alanine produced more DCAN than other org-N compounds regardless of chlorination or chloramination. As for protein targets, genome sequencing is greatly accelerating the identification of human and microbial RNA transcripts for targeted drug discovery. Do health-care decision makers find economic evaluations useful?. Some degree of twin-to-twin transfusion of amniotic fluid was also possible, which could have rescued the oligohydramnios known to be associated with kidney and urinary tract abnormalities. An oligomer of the major outer membrane protein of Chlamydia psittaci is recognized by monoclonal antibodies which protect mice from abortion. Pineoblastoma, a primitive neuroectodermal tumor in the brain of a horse. The technique is easy to perform, avoids the use of radioactive reagents, and is applicable to the detection of any extensive DNA deletion. The resulting gain of vocal efficiency may reduce vocal fatigue and provide a useful adjunct to voice therapy for PRD.

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Twenty-eight severely mentally ill adults in an inner-city area of Atlanta participated in a study to determine if intensive outreach by case managers would result in decreased use of mental hospitals and improved community living. Candida chorioretinitis and endophthalmitis are complications of systemic candidiasis with extension of the fungal pathogens to the uvea and retina. However, the acute onset of vague theolair 250 mg hond midfoot symptomatology secondary to a minor traumatic event may reveal this rarely reported condition on further clinical examination. Clinically, there was anovulation with resultant infertility, which was resistant to therapy with clomiphene citrate. Considerable pain relief and functional improvement was achieved, and only a very small group derived no benefit from the operation. Meiosis-specific gene discovery in plants: RNA-Seq applied to isolated Arabidopsis male meiocytes. In the article the experience in dealing with the affected families in a multidisciplinary context is described. First, will experimental results translate into the real world, where species are being lost at an alarming rate?. Local oxygen supply and blood flow regulation in contracting muscle in dogs and rabbits. Median values of these analytes were compared using the Mann-Whitney U test.

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A total of 39 cochleae, 10 non-exposed and 29 noise exposed cochleae, were analyzed in a scanning electronmicroscope. Psychosocial predictors of hypertension in black and white Africans. This includes their relationship to underlying physiology and pathology, and tracking over time. Influence of coding-end sequence on coding-end processing in V(D)J recombination. These accumulations were immunocytochemically stained with the antibody against cathepsin B, a marker of lysosomal activity, and the staining patterns found with acid phosphatase were similar to those found with cathepsin B. A total of 50 eyes of 25 normal subjects underwent RNFL thickness measurement in 2008 and again in 2011 by a single operator, using spectral OCT/SLO. Inheritance of evolved clethodim resistance in Lolium rigidum populations from Australia. Effects of orchiectomy and polyestradiol phosphate therapy on serum lipoprotein lipids and glucose tolerance in prostatic cancer patients.

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Phylogenetic relationships and demographic histories of the Atherinidae in the Eastern Atlantic and Mediterranean Sea re-examined by Bayesian inference. CSF concentrations of morphine-6-glucuronide after oral administration of morphine. It was found that only the SulA portion of the fusion protein was degraded by Lon protease in an ATP-dependent manner. The direct interaction between miR-144-3p and FN1, which mediates the pro-invasive role of SphK1 in PTC cells, was experimentally validated. To test whether primary care genetic-led genetics education improves both non-cancer and cancer referral rates, and primary care-led genetics clinics improve the patient pathway. Differences in multiple biomechanical waveform parameters between the keratoconus and post-LASIK groups suggests that waveform analysis may be useful to differentiate between healthy and diseased biomechanical what cold medicine can you take with allegra conditions.

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